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MAP9 microtubule associated protein 9 [ Homo sapiens (human) ]

Gene ID: 79884, updated on 16-Jul-2021

Summary

Official Symbol
MAP9provided by HGNC
Official Full Name
microtubule associated protein 9provided by HGNC
Primary source
HGNC:HGNC:26118
See related
Ensembl:ENSG00000164114 MIM:610070
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ASAP
Summary
ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]
Expression
Broad expression in brain (RPKM 7.7), thyroid (RPKM 7.3) and 23 other tissues See more
Orthologs
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Genomic context

See MAP9 in Genome Data Viewer
Location:
4q32.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (155342658..155376970, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (156263810..156298117, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y2 Neighboring gene NPY2R antisense RNA 1 Neighboring gene uncharacterized LOC105377502 Neighboring gene uncharacterized LOC102724776 Neighboring gene TBC1 domain family member 3C pseudogene Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21159

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic spindle assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of mitotic centrosome separation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of mitotic spindle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in astral microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in astral microtubule IDA
Inferred from Direct Assay
more info
PubMed 
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitotic spindle midzone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle midzone IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
microtubule-associated protein 9
Names
aster-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039580.2NP_001034669.1  microtubule-associated protein 9

    See identical proteins and their annotated locations for NP_001034669.1

    Status: VALIDATED

    Source sequence(s)
    AC097467, AY690636, BC022852, CF144347
    Consensus CDS
    CCDS35493.1
    UniProtKB/Swiss-Prot
    Q49MG5
    UniProtKB/TrEMBL
    Q05CN5
    Related
    ENSP00000310593.4, ENST00000311277.9
    Conserved Domains (1) summary
    cl01868
    Location:521597
    YukC; WXG100 protein secretion system (Wss), protein YukC

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    155342658..155376970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011532255.3XP_011530557.1  microtubule-associated protein 9 isoform X3

    Conserved Domains (1) summary
    cl01868
    Location:449525
    YukC; WXG100 protein secretion system (Wss), protein YukC
  2. XM_011532254.2XP_011530556.1  microtubule-associated protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011530556.1

    UniProtKB/Swiss-Prot
    Q49MG5
    Conserved Domains (1) summary
    cl01868
    Location:521597
    YukC; WXG100 protein secretion system (Wss), protein YukC
  3. XM_017008617.1XP_016864106.1  microtubule-associated protein 9 isoform X2

    Conserved Domains (1) summary
    cl01868
    Location:520596
    YukC; WXG100 protein secretion system (Wss), protein YukC
  4. XM_011532253.1XP_011530555.1  microtubule-associated protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011530555.1

    UniProtKB/Swiss-Prot
    Q49MG5
    Conserved Domains (1) summary
    cl01868
    Location:521597
    YukC; WXG100 protein secretion system (Wss), protein YukC
  5. XM_006714306.4XP_006714369.1  microtubule-associated protein 9 isoform X2

    Conserved Domains (1) summary
    cl01868
    Location:520596
    YukC; WXG100 protein secretion system (Wss), protein YukC
  6. XM_017008616.1XP_016864105.1  microtubule-associated protein 9 isoform X2

    Conserved Domains (1) summary
    cl01868
    Location:520596
    YukC; WXG100 protein secretion system (Wss), protein YukC

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_024826.1: Suppressed sequence

    Description
    NM_024826.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
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