Format

Send to:

Choose Destination

TUBAL3 tubulin alpha like 3 [ Homo sapiens (human) ]

Gene ID: 79861, updated on 8-Jul-2021

Summary

Official Symbol
TUBAL3provided by HGNC
Official Full Name
tubulin alpha like 3provided by HGNC
Primary source
HGNC:HGNC:23534
See related
Ensembl:ENSG00000178462
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in small intestine (RPKM 13.2), duodenum (RPKM 10.7) and 2 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TUBAL3 in Genome Data Viewer
Location:
10p15.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (5393101..5404828, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (5435064..5446791, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L26 pseudogene 28 Neighboring gene urocortin 3 Neighboring gene neuroepithelial cell transforming 1 Neighboring gene CRISPRi-validated cis-regulatory element chr10.219

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of tubulin, alpha-like 3 (TUBAL3) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21665, MGC119347, MGC119349

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171864.2NP_001165335.1  tubulin alpha chain-like 3 isoform 2

    See identical proteins and their annotated locations for NP_001165335.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK025318, AL683826, BC098247, DA890426
    Consensus CDS
    CCDS53491.1
    UniProtKB/Swiss-Prot
    A6NHL2
    Related
    ENSP00000418799.1, ENST00000479328.1
    Conserved Domains (1) summary
    cd02186
    Location:13402
    alpha_tubulin; The alpha-tubulin family
  2. NM_024803.3NP_079079.1  tubulin alpha chain-like 3 isoform 1

    See identical proteins and their annotated locations for NP_079079.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK025318, AL683826
    Consensus CDS
    CCDS7066.2
    UniProtKB/Swiss-Prot
    A6NHL2
    Related
    ENSP00000369784.3, ENST00000380419.8
    Conserved Domains (1) summary
    cd02186
    Location:2442
    alpha_tubulin; The alpha-tubulin family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    5393101..5404828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center