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ZBTB3 zinc finger and BTB domain containing 3 [ Homo sapiens (human) ]

Gene ID: 79842, updated on 1-Jun-2020

Summary

Official Symbol
ZBTB3provided by HGNC
Official Full Name
zinc finger and BTB domain containing 3provided by HGNC
Primary source
HGNC:HGNC:22918
See related
Ensembl:ENSG00000185670
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 1.5), skin (RPKM 1.4) and 25 other tissues See more
Orthologs

Genomic context

See ZBTB3 in Genome Data Viewer
Location:
11q12.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (62750963..62754160, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (62518435..62521656, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene HNRNPUL2-BSCL2 readthrough (NMD candidate) Neighboring gene heterogeneous nuclear ribonucleoprotein U like 2 Neighboring gene tetratricopeptide repeat domain 9C Neighboring gene RNA polymerase II subunit G Neighboring gene TATA-box binding protein associated factor 6 like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23392

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to DNA damage stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363108.2NP_001350037.1  zinc finger and BTB domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    AP001160
    Conserved Domains (4) summary
    sd00017
    Location:424444
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:14115
    BTB; BTB/POZ domain
    pfam13465
    Location:437461
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:173401
    Atrophin-1; Atrophin-1 family
  2. NM_001363109.2NP_001350038.1  zinc finger and BTB domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    AP001160
    Conserved Domains (4) summary
    sd00017
    Location:424444
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:14115
    BTB; BTB/POZ domain
    pfam13465
    Location:437461
    zf-H2C2_2; Zinc-finger double domain
    cl26464
    Location:173401
    Atrophin-1; Atrophin-1 family
  3. NM_001370809.1NP_001357738.1  zinc finger and BTB domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    AP001160
    Consensus CDS
    CCDS8034.1
    Related
    ENSP00000378286.4, ENST00000394807.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    62750963..62754160 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_024784.4: Suppressed sequence

    Description
    NM_024784.4: This RefSeq was removed because currently there is support for the transcript but not for the protein.
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