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NAA40 N-alpha-acetyltransferase 40, NatD catalytic subunit [ Homo sapiens (human) ]

Gene ID: 79829, updated on 1-Jun-2020

Summary

Official Symbol
NAA40provided by HGNC
Official Full Name
N-alpha-acetyltransferase 40, NatD catalytic subunitprovided by HGNC
Primary source
HGNC:HGNC:25845
See related
Ensembl:ENSG00000110583
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NatD; NAT11; PATT1; hNatD
Expression
Ubiquitous expression in testis (RPKM 9.3), spleen (RPKM 7.5) and 25 other tissues See more
Orthologs

Genomic context

See NAA40 in Genome Data Viewer
Location:
11q13.1
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (63938973..63957322)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (63706442..63724799)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene microtubule affinity regulating kinase 2 Neighboring gene tRNA-Arg (anticodon CCT) 9-1 Neighboring gene REST corepressor 2 Neighboring gene RNA, U6 small nuclear 45, pseudogene Neighboring gene cytochrome c oxidase subunit 8A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13848

Gene Ontology Provided by GOA

Function Evidence Code Pubs
H2A histone acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
H2A histone acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
H4 histone acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
H4 histone acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
peptide-serine-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptide-serine-N-acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
N-terminal protein amino acid acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
N-terminal protein amino acid acetylation IDA
Inferred from Direct Assay
more info
PubMed 
histone H2A acetylation IDA
Inferred from Direct Assay
more info
PubMed 
histone H4 acetylation IDA
Inferred from Direct Assay
more info
PubMed 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
regulation of chromatin silencing at rDNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-alpha-acetyltransferase 40
Names
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog
N-acetyltransferase 11 (GCN5-related, putative)
N-alpha acetyl transferase 40
N-alpha-acetyltransferase D
natD catalytic subunit
protein acetyltransferase 1
NP_001287729.1
NP_079047.2
XP_006718752.1
XP_011543556.1
XP_011543557.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001300800.1NP_001287729.1  N-alpha-acetyltransferase 40 isoform 2

    See identical proteins and their annotated locations for NP_001287729.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate exon in place of the first exon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AP003780, BC041617, DC307984, HY009487
    Consensus CDS
    CCDS73311.1
    UniProtKB/Swiss-Prot
    Q86UY6
    Related
    ENSP00000442055.1, ENST00000542163.1
    Conserved Domains (1) summary
    pfam00583
    Location:59167
    Acetyltransf_1; Acetyltransferase (GNAT) family
  2. NM_024771.4NP_079047.2  N-alpha-acetyltransferase 40 isoform 1

    See identical proteins and their annotated locations for NP_079047.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AP003780
    Consensus CDS
    CCDS8053.1
    UniProtKB/Swiss-Prot
    Q86UY6
    UniProtKB/TrEMBL
    A0A024R5C6
    Related
    ENSP00000367024.4, ENST00000377793.9
    Conserved Domains (1) summary
    pfam00583
    Location:80188
    Acetyltransf_1; Acetyltransferase (GNAT) family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    63938973..63957322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011545254.2XP_011543556.1  N-alpha-acetyltransferase 40 isoform X1

    Conserved Domains (1) summary
    pfam00583
    Location:180250
    Acetyltransf_1; Acetyltransferase (GNAT) family
  2. XM_011545255.2XP_011543557.1  N-alpha-acetyltransferase 40 isoform X2

    Conserved Domains (1) summary
    pfam00583
    Location:180220
    Acetyltransf_1; Acetyltransferase (GNAT) family
  3. XM_006718689.3XP_006718752.1  N-alpha-acetyltransferase 40 isoform X3

    Conserved Domains (1) summary
    pfam00583
    Location:117157
    Acetyltransf_1; Acetyltransferase (GNAT) family
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