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CATSPERB cation channel sperm associated auxiliary subunit beta [ Homo sapiens (human) ]

Gene ID: 79820, updated on 12-Oct-2019

Summary

Official Symbol
CATSPERBprovided by HGNC
Official Full Name
cation channel sperm associated auxiliary subunit betaprovided by HGNC
Primary source
HGNC:HGNC:20500
See related
Ensembl:ENSG00000133962 MIM:611169
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf161; CatSper(beta)
Expression
Biased expression in testis (RPKM 2.2), gall bladder (RPKM 1.6) and 12 other tissues See more
Orthologs

Genomic context

See CATSPERB in Genome Data Viewer
Location:
14q32.12
Exon count:
27
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (91580698..91732086, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (92046728..92198413, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene protein phosphatase 4 regulatory subunit 3A Neighboring gene uncharacterized LOC101928957 Neighboring gene RNA polymerase III subunit G pseudogene 1 Neighboring gene Nanog homeobox pseudogene 7 Neighboring gene pyruvate dehydrogenase kinase 3 pseudogene Neighboring gene tandem C2 domains, nuclear Neighboring gene fibulin 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

  • Fertilization, organism-specific biosystem (from REACTOME)
    Fertilization, organism-specific biosystemMammalian fertilization comprises sperm migration through the female reproductive tract, biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct. Although the broad c...
  • Reproduction, organism-specific biosystem (from REACTOME)
    Reproduction, organism-specific biosystemHuman reproduction mixes the genomes of two individuals creating a new organism. The offspring individuals produced by sexual reproduction differ from their parents and from their siblings. Reproduct...
  • Sperm Motility And Taxes, organism-specific biosystem (from REACTOME)
    Sperm Motility And Taxes, organism-specific biosystemA series of receptor signaling pathways potentially govern chemical communication between sperm and egg, chemotactically guiding incoming sperm towards the oocyte. Though several substances are confi...

General gene information

Markers

Homology

Clone Names

  • FLJ14298

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
response to progesterone TAS
Traceable Author Statement
more info
 
sperm-egg recognition TAS
Traceable Author Statement
more info
 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
CatSper complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
CatSper complex ISS
Inferred from Sequence or Structural Similarity
more info
 
cilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
cation channel sperm-associated protein subunit beta
Names
catSper-beta
cation channel, sperm associated beta
catsper channel auxiliary subunit beta

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024764.4NP_079040.2  cation channel sperm-associated protein subunit beta precursor

    See identical proteins and their annotated locations for NP_079040.2

    Status: VALIDATED

    Source sequence(s)
    AK126034, AL133373, BC126214, BI559703
    Consensus CDS
    CCDS32142.1
    UniProtKB/Swiss-Prot
    Q9H7T0
    UniProtKB/TrEMBL
    B3KWW9
    Related
    ENSP00000256343.3, ENST00000256343.8
    Conserved Domains (1) summary
    pfam15149
    Location:5691086
    CATSPERB; Cation channel sperm-associated protein subunit beta protein family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    91580698..91732086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187598.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    44834..199881 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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