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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011776.1 RefSeqGene
- Range
-
5014..222136
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001145527.2 → NP_001138999.1 histone-lysine N-methyltransferase EHMT1 isoform 2
See identical proteins and their annotated locations for NP_001138999.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AB028932, BC047504, BM681619
- Consensus CDS
-
CCDS56595.1
- UniProtKB/Swiss-Prot
-
Q9H9B1
- Related
- ENSP00000417328.1, ENST00000462484.5
- Conserved Domains (3) summary
-
- cd00204
Location:742 → 796
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam13637
Location:742 → 793
- Ank_4; Ankyrin repeats (many copies)
- sd00045
Location:742 → 768
- ANK; ANK repeat [structural motif]
-
NM_001354259.2 → NP_001341188.1 histone-lysine N-methyltransferase EHMT1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an exon in the 5' region and differs in the 3' exon structure compared to variant 1. It initiates translation at a downstream start codon. The encoded isoform (3) has a shorter N-terminus and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AK022941, AL590627, AL611925, BC047504
- Conserved Domains (2) summary
-
- cd00204
Location:711 → 802
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:743 → 772
- ANK; ANK repeat [structural motif]
-
NM_001354263.2 → NP_001341192.1 histone-lysine N-methyltransferase EHMT1 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate splice site compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
- Source sequence(s)
-
AL365502, AL590627, AL611925
- Conserved Domains (5) summary
-
- smart00317
Location:1119 → 1241
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:793 → 919
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:798 → 829
- ANK; ANK repeat [structural motif]
- pfam05033
Location:1007 → 1111
- Pre-SET; Pre-SET motif
- cl26073
Location:740 → 999
- Ank_2; Ankyrin repeats (3 copies)
-
NM_001354611.2 → NP_001341540.1 histone-lysine N-methyltransferase EHMT1 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks multiple 3' exons and contains an alternate 3' coding region and 3' UTR compared to variant 1. The encoded isoform (5) has a shorter, distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AL365502, AL590627
- Consensus CDS
-
CCDS87721.1
- UniProtKB/TrEMBL
-
A0A1B0GUD1
- Related
- ENSP00000490056.1, ENST00000629335.2
-
NM_001354612.2 → NP_001341541.1 histone-lysine N-methyltransferase EHMT1 isoform 6
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks an exon in the 5' region, initiates translation at a downstream start codon and differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (6) has a shorter N-terminus and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AL365502, AL590627
- Related
- ENSP00000485900.1, ENST00000626066.2
-
NM_024757.5 → NP_079033.4 histone-lysine N-methyltransferase EHMT1 isoform 1
See identical proteins and their annotated locations for NP_079033.4
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB028932, BC011608, BC047504, CA426038
- Consensus CDS
-
CCDS7050.2
- UniProtKB/Swiss-Prot
- Q96KH4, Q9H9B1
- Related
- ENSP00000417980.1, ENST00000460843.6
- Conserved Domains (4) summary
-
- sd00045
Location:805 → 836
- ANK; ANK repeat [structural motif]
- cd10535
Location:1036 → 1266
- SET_EHMT1; SET domain (including pre-SET and post-SET domains) found in euchromatic histone-lysine N-methyltransferase 1 (EHMT1) and similar proteins
- cd20905
Location:514 → 644
- EHMT_ZBD; Zinc-binding domain of euchromatic histone lysine methyltransferases EHMT1 and EHTM2
- pfam12796
Location:810 → 903
- Ank_2; Ankyrin repeats (3 copies)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000009.12 Reference GRCh38.p14 Primary Assembly
- Range
-
137619005..137836127
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047423872.1 → XP_047279828.1 histone-lysine N-methyltransferase EHMT1 isoform X3
-
XM_047423875.1 → XP_047279831.1 histone-lysine N-methyltransferase EHMT1 isoform X8
-
XM_047423878.1 → XP_047279834.1 histone-lysine N-methyltransferase EHMT1 isoform X10
- UniProtKB/TrEMBL
-
A0A1B0GV09
-
XM_005266110.2 → XP_005266167.1 histone-lysine N-methyltransferase EHMT1 isoform X10
See identical proteins and their annotated locations for XP_005266167.1
- UniProtKB/TrEMBL
-
A0A1B0GV09
- Conserved Domains (6) summary
-
- smart00248
Location:741 → 769
- ANK; ankyrin repeats
- smart00317
Location:1095 → 1217
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:769 → 895
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam05033
Location:983 → 1087
- Pre-SET; Pre-SET motif
- pfam12796
Location:779 → 872
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:774 → 805
- ANK; ANK repeat [structural motif]
-
XM_047423883.1 → XP_047279839.1 histone-lysine N-methyltransferase EHMT1 isoform X15
-
XM_047423881.1 → XP_047279837.1 histone-lysine N-methyltransferase EHMT1 isoform X13
-
XM_017015138.2 → XP_016870627.1 histone-lysine N-methyltransferase EHMT1 isoform X11
-
XM_047423884.1 → XP_047279840.1 histone-lysine N-methyltransferase EHMT1 isoform X16
-
XM_047423882.1 → XP_047279838.1 histone-lysine N-methyltransferase EHMT1 isoform X14
-
XM_047423885.1 → XP_047279841.1 histone-lysine N-methyltransferase EHMT1 isoform X17
-
XM_024447678.2 → XP_024303446.2 histone-lysine N-methyltransferase EHMT1 isoform X19
-
XM_047423886.1 → XP_047279842.1 histone-lysine N-methyltransferase EHMT1 isoform X20
-
XM_047423888.1 → XP_047279844.1 histone-lysine N-methyltransferase EHMT1 isoform X22
-
XM_047423887.1 → XP_047279843.1 histone-lysine N-methyltransferase EHMT1 isoform X21
- Related
- ENSP00000489961.1, ENST00000636027.1
-
XM_047423889.1 → XP_047279845.1 histone-lysine N-methyltransferase EHMT1 isoform X23
-
XM_011519022.4 → XP_011517324.1 histone-lysine N-methyltransferase EHMT1 isoform X2
- Conserved Domains (6) summary
-
- smart00248
Location:774 → 802
- ANK; ankyrin repeats
- smart00317
Location:1128 → 1250
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:802 → 928
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam05033
Location:1016 → 1120
- Pre-SET; Pre-SET motif
- pfam12796
Location:812 → 905
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:807 → 838
- ANK; ANK repeat [structural motif]
-
XM_017015134.2 → XP_016870623.1 histone-lysine N-methyltransferase EHMT1 isoform X5
-
XM_047423873.1 → XP_047279829.1 histone-lysine N-methyltransferase EHMT1 isoform X6
-
XM_047423879.1 → XP_047279835.1 histone-lysine N-methyltransferase EHMT1 isoform X11
-
XM_011519021.4 → XP_011517323.1 histone-lysine N-methyltransferase EHMT1 isoform X1
- Conserved Domains (4) summary
-
- COG0666
Location:765 → 932
- ANKYR; Ankyrin repeat [Signal transduction mechanisms]
- sd00045
Location:808 → 839
- ANK; ANK repeat [structural motif]
- pfam13637
Location:912 → 962
- Ank_4; Ankyrin repeats (many copies)
- cd10535
Location:1039 → 1269
- SET_EHMT1; SET domain (including pre-SET and post-SET domains) found in euchromatic histone-lysine N-methyltransferase 1 (EHMT1) and similar proteins
-
XM_047423880.1 → XP_047279836.1 histone-lysine N-methyltransferase EHMT1 isoform X12
-
XM_047423874.1 → XP_047279830.1 histone-lysine N-methyltransferase EHMT1 isoform X7
-
XM_011519023.4 → XP_011517325.1 histone-lysine N-methyltransferase EHMT1 isoform X4
- Conserved Domains (6) summary
-
- smart00248
Location:768 → 796
- ANK; ankyrin repeats
- smart00317
Location:1122 → 1244
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:796 → 922
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam05033
Location:1010 → 1114
- Pre-SET; Pre-SET motif
- pfam12796
Location:806 → 899
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:801 → 832
- ANK; ANK repeat [structural motif]
-
XM_047423876.1 → XP_047279832.1 histone-lysine N-methyltransferase EHMT1 isoform X9
-
XM_047423877.1 → XP_047279833.1 histone-lysine N-methyltransferase EHMT1 isoform X10
- UniProtKB/TrEMBL
-
A0A1B0GV09
- Related
- ENSP00000490328.1, ENST00000637161.1
-
XM_024447677.2 → XP_024303445.1 histone-lysine N-methyltransferase EHMT1 isoform X18
- Conserved Domains (5) summary
-
- smart00317
Location:834 → 956
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:508 → 634
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:513 → 544
- ANK; ANK repeat [structural motif]
- pfam05033
Location:722 → 826
- Pre-SET; Pre-SET motif
- pfam12796
Location:450 → 544
- Ank_2; Ankyrin repeats (3 copies)
-
XM_011519029.4 → XP_011517331.1 histone-lysine N-methyltransferase EHMT1 isoform X24
- Conserved Domains (6) summary
-
- smart00248
Location:249 → 277
- ANK; ankyrin repeats
- smart00317
Location:603 → 725
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:277 → 403
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam05033
Location:491 → 595
- Pre-SET; Pre-SET motif
- pfam12796
Location:287 → 380
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:282 → 313
- ANK; ANK repeat [structural motif]
-
XM_011519030.4 → XP_011517332.1 histone-lysine N-methyltransferase EHMT1 isoform X25
- Conserved Domains (7) summary
-
- smart00248
Location:199 → 228
- ANK; ankyrin repeats
- smart00317
Location:387 → 509
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:61 → 187
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam05033
Location:275 → 379
- Pre-SET; Pre-SET motif
- pfam12796
Location:71 → 164
- Ank_2; Ankyrin repeats (3 copies)
- pfam13637
Location:54 → 87
- Ank_4; Ankyrin repeats (many copies)
- sd00045
Location:66 → 97
- ANK; ANK repeat [structural motif]
-
XM_047423890.1 → XP_047279846.1 histone-lysine N-methyltransferase EHMT1 isoform X26
-
XM_011519031.2 → XP_011517333.1 histone-lysine N-methyltransferase EHMT1 isoform X26
See identical proteins and their annotated locations for XP_011517333.1
- Conserved Domains (5) summary
-
- smart00317
Location:316 → 438
- SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
- cd00204
Location:23 → 149
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam05033
Location:204 → 308
- Pre-SET; Pre-SET motif
- pfam12796
Location:1 → 93
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:28 → 60
- ANK; ANK repeat [structural motif]
Alternate T2T-CHM13v2.0
Genomic
-
NC_060933.1 Alternate T2T-CHM13v2.0
- Range
-
149870687..150093989
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001039765.1: Suppressed sequence
- Description
- NM_001039765.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.