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HHIPL2 HHIP like 2 [ Homo sapiens (human) ]

Gene ID: 79802, updated on 5-Aug-2022

Summary

Official Symbol
HHIPL2provided by HGNC
Official Full Name
HHIP like 2provided by HGNC
Primary source
HGNC:HGNC:25842
See related
Ensembl:ENSG00000143512 AllianceGenome:HGNC:25842
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KIAA1822L
Summary
Predicted to enable catalytic activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 5.8), bone marrow (RPKM 3.9) and 24 other tissues See more
Orthologs
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Genomic context

See HHIPL2 in Genome Data Viewer
Location:
1q41
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (222522264..222548104, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (221756027..221781870, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (222695606..222721446, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904519 Neighboring gene RNA, U6 small nuclear 791, pseudogene Neighboring gene TATA-box binding protein associated factor, RNA polymerase I subunit A Neighboring gene TAF1A antisense RNA 1 Neighboring gene H3K27me3-DHS negatively-acting regulatory element H1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13840

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
HHIP-like protein 2
Names
hedgehog interacting protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024746.4NP_079022.2  HHIP-like protein 2 precursor

    See identical proteins and their annotated locations for NP_079022.2

    Status: VALIDATED

    Source sequence(s)
    AL592148, AY358602, BC016552, DA868891
    Consensus CDS
    CCDS1530.2
    UniProtKB/Swiss-Prot
    Q6UWX4, Q9H8A0
    Related
    ENSP00000342118.6, ENST00000343410.7
    Conserved Domains (2) summary
    pfam03024
    Location:44182
    Folate_rec; Folate receptor family
    pfam07995
    Location:216464
    GSDH; Glucose / Sorbosone dehydrogenase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    222522264..222548104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449814.2XP_024305582.1  HHIP-like protein 2 isoform X1

    Conserved Domains (2) summary
    pfam03024
    Location:44182
    Folate_rec; Folate receptor family
    cl26817
    Location:216464
    GSDH; Glucose / Sorbosone dehydrogenase
  2. XM_011509986.2XP_011508288.1  HHIP-like protein 2 isoform X2

    Conserved Domains (2) summary
    pfam03024
    Location:44182
    Folate_rec; Folate receptor family
    pfam07995
    Location:216464
    GSDH; Glucose / Sorbosone dehydrogenase

RNA

  1. XR_007063703.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    221756027..221781870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)