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jam3a junctional adhesion molecule 3a [ Danio rerio (zebrafish) ]

Gene ID: 797651, updated on 9-Sep-2025
Official Symbol
jam3aprovided by ZNC
Official Full Name
junctional adhesion molecule 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070424-177
See related
Ensembl:ENSDARG00000114589 AllianceGenome:ZFIN:ZDB-GENE-070424-177
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
jamc.2; si:ch211-277g22.3
Summary
Predicted to enable cell-cell adhesion mediator activity and integrin binding activity. Predicted to be involved in cell migration and cell-cell adhesion. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be part of protein complex involved in cell adhesion. Predicted to be active in cell-cell contact zone and plasma membrane. Is expressed in brain; lateral line primordium; and neural tube. Orthologous to human JAM3 (junctional adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
all
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Location:
chromosome: 15
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 15 NC_133190.1 (21743792..21767345)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 15 NC_007126.7 (19293849..19317134)

Chromosome 15 - NC_133190.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin superfamily, member 9Ba Neighboring gene uncharacterized LOC141377819 Neighboring gene uncharacterized LOC137490507 Neighboring gene VPS26, retromer complex component B Neighboring gene thymocyte nuclear protein 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. A rapid and scalable method for selecting recombinant mouse monoclonal antibodies. Crosnier C, et al. BMC Biol, 2010 Jun 4. PMID 20525357, Free PMC Article
  2. Genetic Mutations in jamb, jamc, and myomaker Revealed Different Roles on Myoblast Fusion and Muscle Growth. Si Y, et al. Mar Biotechnol (NY), 2019 Feb. PMID 30467785, Free PMC Article
  3. Genomic organisation, embryonic expression and biochemical interactions of the zebrafish junctional adhesion molecule family of receptors. Powell GT, et al. PLoS One, 2012. PMID 22815827, Free PMC Article
  4. A benchmarked protein microarray-based platform for the identification of novel low-affinity extracellular protein interactions. Sun Y, et al. Anal Biochem, 2012 May 1. PMID 22342946, Free PMC Article
  5. Sec13 safeguards the integrity of the endoplasmic reticulum and organogenesis of the digestive system in zebrafish. Niu X, et al. Dev Biol, 2012 Jul 15. PMID 22609279

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cell-cell adhesion mediator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
  
is_active_in cell-cell contact zone IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of protein complex involved in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
junctional adhesion molecule 3B-like
Names
JAM-C-like protein
jamc2
junctional adhesion molecule 3

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RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133190.1 Reference GRCz12tu Primary Assembly

    Range
    21743792..21767345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466393.3 → XP_021322068.2  junctional adhesion molecule 3B-like

    UniProtKB/TrEMBL
    A0A8M1Q7B3, A0A8M9P779, F1QYW3
Nucleotide Protein Strain
Heading Accession and Version

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