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TEFM transcription elongation factor, mitochondrial [ Homo sapiens (human) ]

Gene ID: 79736, updated on 3-May-2020

Summary

Official Symbol
TEFMprovided by HGNC
Official Full Name
transcription elongation factor, mitochondrialprovided by HGNC
Primary source
HGNC:HGNC:26223
See related
Ensembl:ENSG00000172171 MIM:616422
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C17orf42
Expression
Ubiquitous expression in kidney (RPKM 3.5), placenta (RPKM 3.5) and 25 other tissues See more
Orthologs

Genomic context

See TEFM in Genome Data Viewer
Location:
17q11.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (30898983..30907629, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (29226001..29233286, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein S17 pseudogene 3 Neighboring gene ATPase family AAA domain containing 5 Neighboring gene RNA, U6 small nuclear 298, pseudogene Neighboring gene ArfGAP with dual PH domains 2 Neighboring gene RNA, 7SL, cytoplasmic 138, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22729, MGC24674

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA polymerase processivity factor activity IDA
Inferred from Direct Assay
more info
PubMed 
RNA binding HDA PubMed 
NOT crossover junction endodeoxyribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA metabolic process IEA
Inferred from Electronic Annotation
more info
 
NOT mitochondrial DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrial transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
oxidative phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription elongation from mitochondrial promoter IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial nucleoid IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
ribonucleoprotein complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transcription elongation factor, mitochondrial
Names
transcription elongation factor of mitochondria

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024683.4NP_078959.3  transcription elongation factor, mitochondrial

    See identical proteins and their annotated locations for NP_078959.3

    Status: VALIDATED

    Source sequence(s)
    AJ314645, BQ003763, DA647699
    Consensus CDS
    CCDS42291.1
    UniProtKB/Swiss-Prot
    Q96QE5
    Related
    ENSP00000462963.1, ENST00000581216.6
    Conserved Domains (1) summary
    cl22429
    Location:77119
    HHH_5; Helix-hairpin-helix domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    30898983..30907629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006722084.2XP_006722147.1  transcription elongation factor, mitochondrial isoform X1

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