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IGFLR1 IGF like family receptor 1 [ Homo sapiens (human) ]

Gene ID: 79713, updated on 23-Nov-2021

Summary

Official Symbol
IGFLR1provided by HGNC
Official Full Name
IGF like family receptor 1provided by HGNC
Primary source
HGNC:HGNC:23620
See related
Ensembl:ENSG00000126246 MIM:614143
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TMEM149
Expression
Broad expression in lymph node (RPKM 16.7), spleen (RPKM 14.5) and 24 other tissues See more
Orthologs
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Genomic context

See IGFLR1 in Genome Data Viewer
Location:
19q13.12
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (35738801..35742452, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (36229702..36233353, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene thymidylate synthetase pseudogene 2 Neighboring gene zinc finger and BTB domain containing 32 Neighboring gene lysine methyltransferase 2B Neighboring gene U2 small nuclear RNA auxiliary factor 1 like 4 Neighboring gene presenilin enhancer, gamma-secretase subunit

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ22573

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
IGF-like family receptor 1
Names
transmembrane protein 149

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001346003.2NP_001332932.1  IGF-like family receptor 1 isoform b precursor

    Status: VALIDATED

    Source sequence(s)
    AD000671
    Consensus CDS
    CCDS86752.1
    UniProtKB/TrEMBL
    K7EL86
    Related
    ENSP00000465962.1, ENST00000588992.5
  2. NM_001346004.2NP_001332933.1  IGF-like family receptor 1 isoform c precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variant 4, encodes isoform c.
    Source sequence(s)
    AD000671
    Consensus CDS
    CCDS86751.1
    UniProtKB/Swiss-Prot
    Q9H665
    Related
    ENSP00000467750.1, ENST00000592889.1
  3. NM_001346005.2NP_001332934.1  IGF-like family receptor 1 isoform c precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variant 3, encodes isoform c.
    Source sequence(s)
    AD000671
    Consensus CDS
    CCDS86751.1
    UniProtKB/Swiss-Prot
    Q9H665
  4. NM_001346006.2NP_001332935.1  IGF-like family receptor 1 isoform d precursor

    Status: VALIDATED

    Source sequence(s)
    AD000671
  5. NM_024660.4NP_078936.1  IGF-like family receptor 1 isoform a precursor

    See identical proteins and their annotated locations for NP_078936.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    AD000671, AK026226, BU621457
    Consensus CDS
    CCDS12472.1
    UniProtKB/Swiss-Prot
    Q9H665
    Related
    ENSP00000246532.1, ENST00000246532.6

RNA

  1. NR_144338.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AD000671, AK026226, BC144205, BU621457
  2. NR_144339.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AD000671
  3. NR_144340.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AD000671
  4. NR_144341.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AD000671
  5. NR_144342.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AD000671

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    35738801..35742452 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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