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NOL9 nucleolar protein 9 [ Homo sapiens (human) ]

Gene ID: 79707, updated on 23-Nov-2021

Summary

Official Symbol
NOL9provided by HGNC
Official Full Name
nucleolar protein 9provided by HGNC
Primary source
HGNC:HGNC:26265
See related
Ensembl:ENSG00000162408
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Grc3; NET6
Expression
Ubiquitous expression in spleen (RPKM 3.0), bone marrow (RPKM 2.3) and 25 other tissues See more
Orthologs
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Genomic context

See NOL9 in Genome Data Viewer
Location:
1p36.31
Exon count:
13
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (6521347..6554535, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (6581407..6614573, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 25 Neighboring gene pleckstrin homology and RhoGEF domain containing G5 Neighboring gene Sharpr-MPRA regulatory region 5048 Neighboring gene RNA, U6 small nuclear 731, pseudogene Neighboring gene taste 1 receptor member 1 Neighboring gene uncharacterized LOC107984912 Neighboring gene zinc finger and BTB domain containing 48

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23323, MGC131821, MGC138483

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding TAS
Traceable Author Statement
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables polynucleotide 5'-hydroxyl-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables polynucleotide 5'-hydroxyl-kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in maturation of 5.8S rRNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in intermediate filament cytoskeleton IDA
Inferred from Direct Assay
more info
 
located_in membrane HDA PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 
located_in nucleolus TAS
Traceable Author Statement
more info
PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
polynucleotide 5'-hydroxyl-kinase NOL9
Names
polynucleotide 5'-kinase
NP_078930.4
XP_005263550.1
XP_011540449.1
XP_016857826.1
XP_016857827.1
XP_016857828.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024654.5NP_078930.4  polynucleotide 5'-hydroxyl-kinase NOL9

    Status: VALIDATED

    Source sequence(s)
    AL591866
    Consensus CDS
    CCDS80.1
    Related
    ENSP00000366934.5, ENST00000377705.6
    Conserved Domains (1) summary
    pfam16575
    Location:306415
    CLP1_P; mRNA cleavage and polyadenylation factor CLP1 P-loop

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    6521347..6554535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017002338.2XP_016857827.1  polynucleotide 5'-hydroxyl-kinase NOL9 isoform X3

    UniProtKB/Swiss-Prot
    Q5SY16
    Conserved Domains (1) summary
    cl38936
    Location:345
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_017002339.2XP_016857828.1  polynucleotide 5'-hydroxyl-kinase NOL9 isoform X3

    UniProtKB/Swiss-Prot
    Q5SY16
    Conserved Domains (1) summary
    cl38936
    Location:345
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_005263493.4XP_005263550.1  polynucleotide 5'-hydroxyl-kinase NOL9 isoform X2

    Conserved Domains (1) summary
    pfam16575
    Location:19128
    CLP1_P; mRNA cleavage and polyadenylation factor CLP1 P-loop
  4. XM_011542147.3XP_011540449.1  polynucleotide 5'-hydroxyl-kinase NOL9 isoform X3

    See identical proteins and their annotated locations for XP_011540449.1

    UniProtKB/Swiss-Prot
    Q5SY16
    Conserved Domains (1) summary
    cl38936
    Location:345
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. XM_017002337.2XP_016857826.1  polynucleotide 5'-hydroxyl-kinase NOL9 isoform X1

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