Format

Send to:

Choose Destination

ZYG11B zyg-11 family member B, cell cycle regulator [ Homo sapiens (human) ]

Gene ID: 79699, updated on 4-Nov-2018

Summary

Official Symbol
ZYG11Bprovided by HGNC
Official Full Name
zyg-11 family member B, cell cycle regulatorprovided by HGNC
Primary source
HGNC:HGNC:25820
See related
Ensembl:ENSG00000162378 Vega:OTTHUMG00000008938
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZYG11
Expression
Ubiquitous expression in brain (RPKM 12.1), thyroid (RPKM 8.7) and 25 other tissues See more
Orthologs

Genomic context

See ZYG11B in Genome Data Viewer
Location:
1p32.3
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (52726454..52827342)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (53192126..53293014)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit S5 pseudogene 3 Neighboring gene RNA, 7SL, cytoplasmic 62, pseudogene Neighboring gene RNA, U2 small nuclear 30, pseudogene Neighboring gene ribosomal protein S13 pseudogene 2 Neighboring gene RNA, U6 small nuclear 969, pseudogene Neighboring gene zyg-11 family member A, cell cycle regulator Neighboring gene enoyl-CoA hydratase domain containing 2 Neighboring gene translation machinery-associated protein 7 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13456

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
regulation of ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Cul2-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein zyg-11 homolog B
Names
zyg-11 homolog B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024646.2NP_078922.1  protein zyg-11 homolog B

    See identical proteins and their annotated locations for NP_078922.1

    Status: VALIDATED

    Source sequence(s)
    AB051517, AC099784, AK296460, AL139255
    Consensus CDS
    CCDS30717.1
    UniProtKB/Swiss-Prot
    Q9C0D3
    UniProtKB/TrEMBL
    B4DK95
    Related
    ENSP00000294353.6, OTTHUMP00000010491, ENST00000294353.6, OTTHUMT00000024749
    Conserved Domains (2) summary
    sd00034
    Location:188213
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl26161
    Location:177299
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

    Range
    52726454..52827342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017002336.2XP_016857825.1  protein zyg-11 homolog B isoform X2

    UniProtKB/TrEMBL
    A8DPD7
    Related
    ENSP00000441315.1, ENST00000545132.5
    Conserved Domains (1) summary
    sd00034
    Location:188213
    LRR_AMN1; leucine-rich repeat [structural motif]
  2. XM_006710898.4XP_006710961.1  protein zyg-11 homolog B isoform X1

    Conserved Domains (3) summary
    cd00020
    Location:489607
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00116
    Location:173295
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:184209
    LRR_AMN1; leucine-rich repeat [structural motif]
Support Center