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RIOX1 ribosomal oxygenase 1 [ Homo sapiens (human) ]

Gene ID: 79697, updated on 25-Nov-2021

Summary

Official Symbol
RIOX1provided by HGNC
Official Full Name
ribosomal oxygenase 1provided by HGNC
Primary source
HGNC:HGNC:20968
See related
Ensembl:ENSG00000170468 MIM:611919
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ROX; NO66; JMJD9; MAPJD; URLC2; hsNO66; C14orf169
Orthologs
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Genomic context

See RIOX1 in Genome Data Viewer
Location:
14q24.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (73490933..73493394)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (73957638..73960098)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene NUMB endocytic adaptor protein Neighboring gene uncharacterized LOC101928143 Neighboring gene HEAT repeat containing 4 Neighboring gene acyl-CoA thioesterase 1 Neighboring gene 5',3'-nucleotidase, cytosolic pseudogene 2 Neighboring gene 5',3'-nucleotidase, cytosolic pseudogene 1 Neighboring gene acyl-CoA thioesterase 2

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21802

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 2-oxoglutarate-dependent dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 2-oxoglutarate-dependent dioxygenase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables histone H3-di/monomethyl-lysine-36 demethylase activity IEA
Inferred from Electronic Annotation
more info
 
enables histone H3-methyl-lysine-36 demethylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone H3-methyl-lysine-36 demethylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables histone H3-methyl-lysine-4 demethylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone H3-tri/di/monomethyl-lysine-4 demethylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables iron ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in histone H3-K36 demethylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in histone H3-K36 demethylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in histone H3-K4 demethylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in histone H3-K4 demethylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in histone H3-K4 demethylation, trimethyl-H3-K4-specific IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
ribosomal oxygenase 1
Names
60S ribosomal protein L8 histidine hydroxylase
MYC-associated protein with JmjC domain
bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
histone lysine demethylase NO66
lysine-specific demethylase NO66
nucleolar protein 66
ribosomal oxygenase NO66
up-regulated in lung cancer 2
NP_078920.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024644.5NP_078920.2  ribosomal oxygenase 1

    See identical proteins and their annotated locations for NP_078920.2

    Status: VALIDATED

    Source sequence(s)
    AC005280, BC071954, BX390965, CN259773, DA509240, DA872764, HY178771
    Consensus CDS
    CCDS73660.1
    UniProtKB/Swiss-Prot
    Q9H6W3
    Related
    ENSP00000477507.1, ENST00000304061.8
    Conserved Domains (1) summary
    pfam08007
    Location:215557
    Cupin_4; Cupin superfamily protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    73490933..73493394
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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