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ZNF322 zinc finger protein 322 [ Homo sapiens (human) ]

Gene ID: 79692, updated on 12-Oct-2019

Summary

Official Symbol
ZNF322provided by HGNC
Official Full Name
zinc finger protein 322provided by HGNC
Primary source
HGNC:HGNC:23640
See related
Ensembl:ENSG00000181315 MIM:610847
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCG12; ZNF388; ZNF489; ZNF322A
Summary
ZNF322A is a member of the zinc-finger transcription factor family and may regulate transcriptional activation in MAPK (see MAPK1; MIM 176948) signaling pathways (Li et al., 2004 [PubMed 15555580]).[supplied by OMIM, Mar 2008]
Expression
Ubiquitous expression in endometrium (RPKM 9.4), thyroid (RPKM 9.3) and 24 other tissues See more
Orthologs

Genomic context

See ZNF322 in Genome Data Viewer
Location:
6p22.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (26634383..26659752, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (26634611..26659980, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374989 Neighboring gene vomeronasal 1 receptor 14 pseudogene Neighboring gene uncharacterized LOC102724851 Neighboring gene uncharacterized LOC105374991 Neighboring gene tRNA-Met (anticodon CAT) 5-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23393

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity, RNA polymerase II-specific NAS
Non-traceable Author Statement
more info
PubMed 
enhancer binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
positive regulation of stem cell population maintenance IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
centrosome IDA
Inferred from Direct Assay
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
zinc finger protein 322
Names
HLA complex group 12
zinc finger protein 322A
zinc finger protein 388
zinc finger protein 489

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242797.1NP_001229726.1  zinc finger protein 322

    See identical proteins and their annotated locations for NP_001229726.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AL513548, DA481584
    Consensus CDS
    CCDS4617.1
    UniProtKB/Swiss-Prot
    Q6U7Q0
    UniProtKB/TrEMBL
    A0A024QZZ4
    Related
    ENSP00000482607.1, ENST00000622479.4
    Conserved Domains (3) summary
    COG5048
    Location:69219
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:207291
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:129149
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001242798.1NP_001229727.1  zinc finger protein 322

    See identical proteins and their annotated locations for NP_001229727.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AL513548, DA437716
    Consensus CDS
    CCDS4617.1
    UniProtKB/Swiss-Prot
    Q6U7Q0
    UniProtKB/TrEMBL
    A0A024QZZ4
    Related
    ENSP00000483223.1, ENST00000607204.5
    Conserved Domains (3) summary
    COG5048
    Location:69219
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:207291
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:129149
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001242799.1NP_001229728.1  zinc finger protein 322

    See identical proteins and their annotated locations for NP_001229728.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AL513548, DB454351
    Consensus CDS
    CCDS4617.1
    UniProtKB/Swiss-Prot
    Q6U7Q0
    UniProtKB/TrEMBL
    A0A024QZZ4
    Related
    ENSP00000478899.1, ENST00000456172.5
    Conserved Domains (3) summary
    COG5048
    Location:69219
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:207291
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:129149
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_024639.5NP_078915.2  zinc finger protein 322

    See identical proteins and their annotated locations for NP_078915.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AK290038, AL513548, BX474628
    Consensus CDS
    CCDS4617.1
    UniProtKB/Swiss-Prot
    Q6U7Q0
    UniProtKB/TrEMBL
    A0A024QZZ4
    Related
    ENSP00000418897.1, ENST00000415922.7
    Conserved Domains (3) summary
    COG5048
    Location:69219
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:207291
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:129149
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    26634383..26659752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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