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MSANTD2 Myb/SANT DNA binding domain containing 2 [ Homo sapiens (human) ]

Gene ID: 79684, updated on 1-Jun-2020

Summary

Official Symbol
MSANTD2provided by HGNC
Official Full Name
Myb/SANT DNA binding domain containing 2provided by HGNC
Primary source
HGNC:HGNC:26266
See related
Ensembl:ENSG00000120458
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C11orf61
Expression
Ubiquitous expression in thyroid (RPKM 1.6), endometrium (RPKM 1.2) and 25 other tissues See more
Orthologs

Genomic context

See MSANTD2 in Genome Data Viewer
Location:
11q24.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (124766492..124800972, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (124636388..124670868, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10895 Neighboring gene uncharacterized LOC101929340 Neighboring gene endothelial cell adhesion molecule Neighboring gene uncharacterized LOC100507283 Neighboring gene E3 ubiquitin-protein ligase RNF181 pseudogene Neighboring gene roundabout guidance receptor 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23342

General protein information

Preferred Names
myb/SANT-like DNA-binding domain-containing protein 2
Names
Myb/SANT-like DNA-binding domain containing 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308027.2NP_001294956.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform 3

    See identical proteins and their annotated locations for NP_001294956.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes the longest isoform (3).
    Source sequence(s)
    AK026995, AP000866, BC064919, DA379833, H97225
    Consensus CDS
    CCDS76491.1
    UniProtKB/Swiss-Prot
    Q6P1R3
    Related
    ENSP00000364118.3, ENST00000374979.7
    Conserved Domains (1) summary
    pfam13837
    Location:104195
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  2. NM_001312919.2NP_001299848.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon that results in a frameshift in the 3' coding region and differences in the 3' UTR, compared to variant 3. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 3.
    Source sequence(s)
    AK026995, AK303902, AL512691, AP000866, BC064919, DA379833
    Consensus CDS
    CCDS81641.1
    UniProtKB/Swiss-Prot
    Q6P1R3
    UniProtKB/TrEMBL
    B4E1M0
    Related
    ENSP00000431707.1, ENST00000524950.1
    Conserved Domains (1) summary
    pfam13837
    Location:104170
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
  3. NM_001312920.1NP_001299849.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 3. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 3. Variants 5-8 all encode the same isoform (2).
    Source sequence(s)
    AK026995, AL512691, BC064919
    Consensus CDS
    CCDS73408.1
    UniProtKB/Swiss-Prot
    Q6P1R3
    Related
    ENSP00000435705.1, ENST00000526629.1
  4. NM_001312921.2NP_001299850.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) uses an alternate splice site in an internal exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 3. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 3. Variants 5-8 all encode the same isoform (2).
    Source sequence(s)
    AK026995, AL512691, AP000866, BC064919, CX781748, DA379833
    Consensus CDS
    CCDS73408.1
    UniProtKB/Swiss-Prot
    Q6P1R3
  5. NM_001352400.2NP_001339329.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 5, 6, and 8, encodes isoform 2.
    Source sequence(s)
    AP000866
    Consensus CDS
    CCDS73408.1
  6. NM_001352401.2NP_001339330.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 5, 6, and 7, encodes isoform 2.
    Source sequence(s)
    AP000866
    Consensus CDS
    CCDS73408.1
  7. NM_024631.4NP_078907.2  myb/SANT-like DNA-binding domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_078907.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate in-frame splice site in an internal exon, compared to variant 3, resulting in an isoform (1) that is shorter than isoform 3.
    Source sequence(s)
    AK026995, AL512691, AP000866, DA379833, H97225
    Consensus CDS
    CCDS8454.1
    UniProtKB/Swiss-Prot
    Q6P1R3
    Related
    ENSP00000239614.4, ENST00000239614.8
    Conserved Domains (1) summary
    pfam13837
    Location:104172
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    124766492..124800972 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017018298.2XP_016873787.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform X3

    UniProtKB/Swiss-Prot
    Q6P1R3
  2. XM_017018297.1XP_016873786.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform X3

    UniProtKB/Swiss-Prot
    Q6P1R3
    Related
    ENST00000650095.1
  3. XM_006718905.2XP_006718968.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_006718968.1

    UniProtKB/Swiss-Prot
    Q6P1R3
  4. XM_017018296.2XP_016873785.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform X3

    UniProtKB/Swiss-Prot
    Q6P1R3
  5. XM_006718906.3XP_006718969.1  myb/SANT-like DNA-binding domain-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_006718969.1

    UniProtKB/Swiss-Prot
    Q6P1R3
  6. XM_011542981.3XP_011541283.2  myb/SANT-like DNA-binding domain-containing protein 2 isoform X1

  7. XM_011542982.3XP_011541284.2  myb/SANT-like DNA-binding domain-containing protein 2 isoform X2

  8. XM_005271674.4XP_005271731.3  myb/SANT-like DNA-binding domain-containing protein 2 isoform X4

    Conserved Domains (1) summary
    pfam13837
    Location:193263
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RNA

  1. XR_002957196.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001301087.1: Suppressed sequence

    Description
    NM_001301087.1: This RefSeq was removed because currently there is insufficient support for the transcript.
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