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C3orf52 chromosome 3 open reading frame 52 [ Homo sapiens (human) ]

Gene ID: 79669, updated on 28-Jan-2023

Summary

Official Symbol
C3orf52provided by HGNC
Official Full Name
chromosome 3 open reading frame 52provided by HGNC
Primary source
HGNC:HGNC:26255
See related
Ensembl:ENSG00000114529 MIM:611956; AllianceGenome:HGNC:26255
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TTMP; HYPT15
Summary
Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in skin (RPKM 9.2), thyroid (RPKM 5.4) and 15 other tissues See more
Orthologs
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Genomic context

See C3orf52 in Genome Data Viewer
Location:
3q13.2
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (112086389..112136381)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (114807509..114839325)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (111805236..111837057)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene riboflavin kinase-like Neighboring gene transmembrane serine protease 7 Neighboring gene microRNA 567 Neighboring gene germinal center associated signaling and motility Neighboring gene TGF-beta induced lncRNA Neighboring gene solute carrier family 9 member C1 Neighboring gene uncharacterized LOC124909407 Neighboring gene INAVA pseudogene 1 Neighboring gene ubiquitination factor E4A (UFD2 homolog, yeast) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23186

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
TPA-induced transmembrane protein
Names
TPA induced trans-membrane protein
novel endoplasmic reticulum transmembrane protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171747.2NP_001165218.1  TPA-induced transmembrane protein isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the shorter transcript but encodes the longer isoform (1).
    Source sequence(s)
    AC128688, AK298076, AK303588
    Consensus CDS
    CCDS54620.1
    UniProtKB/Swiss-Prot
    Q5BVD1
    Related
    ENSP00000399392.2, ENST00000431717.6
  2. NM_024616.3NP_078892.3  TPA-induced transmembrane protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has two additional coding exons in the 3' region, as compared to variant 1. The resulting isoform (2) is shorter and has a different C-terminus, as compared to isoform 1.
    Source sequence(s)
    AC024887, AC128688
    Consensus CDS
    CCDS46887.1
    UniProtKB/Swiss-Prot
    Q9H5Q1
    Related
    ENSP00000264848.5, ENST00000264848.10

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    112086389..112136381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_924171.4 RNA Sequence

  2. XR_007095726.1 RNA Sequence

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_019805492.1 Reference GRCh38.p14 PATCHES

    Range
    1..1500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    114807509..114839325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)