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AKIRIN1 akirin 1 [ Homo sapiens (human) ]

Gene ID: 79647, updated on 13-Mar-2020

Summary

Official Symbol
AKIRIN1provided by HGNC
Official Full Name
akirin 1provided by HGNC
Primary source
HGNC:HGNC:25744
See related
Ensembl:ENSG00000174574 MIM:615164
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
STRF2; C1orf108
Expression
Ubiquitous expression in testis (RPKM 41.1), bone marrow (RPKM 25.3) and 25 other tissues See more
Orthologs

Genomic context

See AKIRIN1 in Genome Data Viewer
Location:
1p34.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (38991244..39006065)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (39456916..39471737)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene rhomboid like 2 Neighboring gene RNA, U6 small nuclear 605, pseudogene Neighboring gene eukaryotic translation initiation factor 1 pseudogene 2 Neighboring gene NADH:ubiquinone oxidoreductase subunit S5 Neighboring gene microtubule actin crosslinking factor 1 Neighboring gene RNA, U6 small nuclear 608, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12666

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
myoblast migration involved in skeletal muscle regeneration ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of satellite cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of skeletal muscle satellite cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of lamellipodium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of macrophage chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of myoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
nuclear membrane IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136275.1NP_001129747.1  akirin-1 isoform 2

    See identical proteins and their annotated locations for NP_001129747.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AK303098, AL606465, DB727813
    Consensus CDS
    CCDS44113.1
    UniProtKB/Swiss-Prot
    Q9H9L7
    Related
    ENSP00000389866.2, ENST00000446189.6
  2. NM_024595.3NP_078871.1  akirin-1 isoform 1

    See identical proteins and their annotated locations for NP_078871.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL606465, BC119745, DB727813
    Consensus CDS
    CCDS433.1
    UniProtKB/Swiss-Prot
    Q9H9L7
    Related
    ENSP00000392678.3, ENST00000432648.8

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    38991244..39006065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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