adrm1 ADRM1 26S proteasome ubiquitin receptor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: adrm1provided by ZNC
Official Full Name: ADRM1 26S proteasome ubiquitin receptorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-905
See related: Ensembl:ENSDARG00000058560 AllianceGenome:ZFIN:ZDB-GENE-040426-905
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: adrm1a; adrm1b; fa12d09; zgc:56107; zgc:77256; wu:fa10g10; wu:fa12d09
Summary: Predicted to enable endopeptidase activator activity and proteasome binding activity. Predicted to be involved in proteasome assembly. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Orthologous to human ADRM1 (ADRM1 26S proteasome ubiquitin receptor). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 23

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	23	NC_133198.1 (9691035..9697365)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (9560975..9567306)

Chromosome 23 - NC_133198.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fa10g10.s1 (e-PCR)
- UniSTS:188804

AA494559 (e-PCR)
- UniSTS:186778

fj03g05.y1 (e-PCR)
- UniSTS:198325

fa06e12.s1 (e-PCR)
- UniSTS:202230

fa26c11.s1 (e-PCR)
- UniSTS:202487

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables endopeptidase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables endopeptidase activator activity	ISS Inferred from Sequence or Structural Similarity more info
enables proteasome binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in proteasome assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome complex	ISS Inferred from Sequence or Structural Similarity more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: proteasomal ubiquitin receptor ADRM1

Names: adhesion regulating molecule 1; adhesion regulating molecule 1a; adhesion regulating molecule 1b

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201013.3 → NP_957307.3 proteasomal ubiquitin receptor ADRM1

Status: VALIDATED

Source sequence(s)

EB796887, EH561147, EH594482

UniProtKB/TrEMBL

A0A8M1PDW7, E9QJJ5

Related

ENSDARP00000108594.2, ENSDART00000130069.4

Conserved Domains (3) summary

cd13314
Location:23 → 127

PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13

pfam08690
Location:220 → 306

GET2; GET complex subunit GET2

pfam16550
Location:277 → 384

RPN13_C; UCH-binding domain

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

NC_133198.1 Reference GRCz12tu Primary Assembly

Range

9691035..9697365

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005161962.6 → XP_005162019.1 proteasomal ubiquitin receptor ADRM1 isoform X1

See identical proteins and their annotated locations for XP_005162019.1

UniProtKB/TrEMBL

A0A8M2B8S2, A8WGS1

Related

ENSDARP00000075874.5

Conserved Domains (3) summary

cd13314
Location:23 → 127

PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13

pfam08690
Location:222 → 308

GET2; GET complex subunit GET2

pfam16550
Location:279 → 386

RPN13_C; UCH-binding domain
XM_021469854.3 → XP_021325529.1 proteasomal ubiquitin receptor ADRM1 isoform X2

UniProtKB/Swiss-Prot

Q6NZ09

UniProtKB/TrEMBL

A0A8M9PKV4

Related

ENSDARP00000113720.1

Conserved Domains (3) summary

cd13314
Location:23 → 127

PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13

pfam16550
Location:278 → 385

RPN13_C; UCH-binding domain

cl28408
Location:221 → 296

UBQ; Ubiquitin homologues