Format

Send to:

Choose Destination

FAM184A family with sequence similarity 184 member A [ Homo sapiens (human) ]

Gene ID: 79632, updated on 7-Oct-2019

Summary

Official Symbol
FAM184Aprovided by HGNC
Official Full Name
family with sequence similarity 184 member Aprovided by HGNC
Primary source
HGNC:HGNC:20991
See related
Ensembl:ENSG00000111879
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf60
Expression
Broad expression in testis (RPKM 10.2), placenta (RPKM 7.8) and 17 other tissues See more
Orthologs

Genomic context

See FAM184A in Genome Data Viewer
Location:
6q22.31
Exon count:
19
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (118959763..119149193, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (119280992..119470552, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene selenoprotein K pseudogene 3 Neighboring gene minichromosome maintenance 9 homologous recombination repair factor Neighboring gene anti-silencing function 1A histone chaperone Neighboring gene microRNA 548b Neighboring gene mannosidase alpha class 1A member 1 Neighboring gene uncharacterized LOC107986526 Neighboring gene ribosomal protein L13a pseudogene 15

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13942

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
extracellular space HDA PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100411.2NP_001093881.1  protein FAM184A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding regions, initiates translation at a downstream start codon and lacks an alternate in-frame exon in the 3' coding region, compared to isoform 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK091682, AU160036, BX538186, DA717412
    Consensus CDS
    CCDS43500.1
    UniProtKB/Swiss-Prot
    Q8NB25
    Related
    ENSP00000326608.6, ENST00000352896.9
    Conserved Domains (4) summary
    TIGR02168
    Location:105822
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam01496
    Location:38126
    V_ATPase_I; V-type ATPase 116kDa subunit family
    pfam15665
    Location:1144
    FAM184; Family with sequence similarity 184, A and B
    cl19219
    Location:399516
    DUF342; Protein of unknown function (DUF342)
  2. NM_001288576.1NP_001275505.1  protein FAM184A isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding regions, initiates translation at a downstream start codon and lacks two alternate in-frame exons in the 3' coding region, compared to isoform 1. It encodes isoform 3, which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK091682, AU160036, BC060769, DA717412
    Consensus CDS
    CCDS75508.1
    UniProtKB/Swiss-Prot
    Q8NB25
    UniProtKB/TrEMBL
    H7BY63, Q6P9G8
    Related
    ENSP00000357460.4, ENST00000368475.8
    Conserved Domains (4) summary
    TIGR02168
    Location:105822
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam01496
    Location:38126
    V_ATPase_I; V-type ATPase 116kDa subunit family
    pfam15665
    Location:1144
    FAM184; Family with sequence similarity 184, A and B
    cl19219
    Location:399516
    DUF342; Protein of unknown function (DUF342)
  3. NM_024581.6NP_078857.5  protein FAM184A isoform 1

    See identical proteins and their annotated locations for NP_078857.5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AI457286, AL132874, AL137009, AU160036, BC060769, DB237883
    Consensus CDS
    CCDS43499.1
    UniProtKB/Swiss-Prot
    Q8NB25
    UniProtKB/TrEMBL
    Q6P9G8
    Related
    ENSP00000342604.7, ENST00000338891.12
    Conserved Domains (4) summary
    TIGR02168
    Location:2271002
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam01496
    Location:158246
    V_ATPase_I; V-type ATPase 116kDa subunit family
    pfam15665
    Location:54264
    FAM184; Family with sequence similarity 184, A and B
    cl19219
    Location:519636
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    118959763..119149193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center