U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ARMH3 armadillo like helical domain containing 3 [ Homo sapiens (human) ]

Gene ID: 79591, updated on 13-Oct-2022

Summary

Official Symbol
ARMH3provided by HGNC
Official Full Name
armadillo like helical domain containing 3provided by HGNC
Primary source
HGNC:HGNC:25788
See related
Ensembl:ENSG00000120029 AllianceGenome:HGNC:25788
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf76
Summary
Involved in regulation of Golgi organization. Located in Golgi membrane and cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart (RPKM 8.1), esophagus (RPKM 4.9) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ARMH3 in Genome Data Viewer
Location:
10q24.32
Exon count:
33
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (101845599..102056173, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (102729087..102941185, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (103605356..103815930, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 4495 Neighboring gene KCNIP2 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 3638 Neighboring gene uncharacterized LOC101927445 Neighboring gene potassium voltage-gated channel interacting protein 2 Neighboring gene uncharacterized LOC124902492 Neighboring gene HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 Neighboring gene LIM domain binding 1 Neighboring gene PPARG related coactivator 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
EBI GWAS Catalog
Genetics of coronary artery calcification among African Americans, a meta-analysis.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13114, MGC125927

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of Golgi organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
armadillo-like helical domain-containing protein 3
Names
UPF0668 protein C10orf76

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024541.3NP_078817.2  armadillo-like helical domain-containing protein 3

    See identical proteins and their annotated locations for NP_078817.2

    Status: VALIDATED

    Source sequence(s)
    AK023176, AK097972, AW936405, DA020448, DA311439, DR002231, DT932690
    Consensus CDS
    CCDS41563.1
    UniProtKB/Swiss-Prot
    Q5T2E6, Q9H8Z9
    UniProtKB/TrEMBL
    B3KUU6
    Related
    ENSP00000359050.4, ENST00000370033.9
    Conserved Domains (1) summary
    pfam08427
    Location:441669
    DUF1741; Domain of unknown function (DUF1741)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    101845599..102056173 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047425735.1XP_047281691.1  armadillo-like helical domain-containing protein 3 isoform X9

  2. XM_011540157.3XP_011538459.1  armadillo-like helical domain-containing protein 3 isoform X5

    Conserved Domains (1) summary
    pfam08427
    Location:390618
    DUF1741; Domain of unknown function (DUF1741)
  3. XM_011540154.3XP_011538456.1  armadillo-like helical domain-containing protein 3 isoform X7

    See identical proteins and their annotated locations for XP_011538456.1

    Conserved Domains (1) summary
    pfam08427
    Location:385613
    DUF1741; Domain of unknown function (DUF1741)
  4. XM_047425737.1XP_047281693.1  armadillo-like helical domain-containing protein 3 isoform X11

  5. XM_011540153.3XP_011538455.1  armadillo-like helical domain-containing protein 3 isoform X4

    See identical proteins and their annotated locations for XP_011538455.1

    Conserved Domains (1) summary
    pfam08427
    Location:407635
    DUF1741; Domain of unknown function (DUF1741)
  6. XM_047425736.1XP_047281692.1  armadillo-like helical domain-containing protein 3 isoform X10

  7. XM_011540152.3XP_011538454.1  armadillo-like helical domain-containing protein 3 isoform X2

    See identical proteins and their annotated locations for XP_011538454.1

    Conserved Domains (1) summary
    pfam08427
    Location:419647
    DUF1741; Domain of unknown function (DUF1741)
  8. XM_006717969.1XP_006718032.1  armadillo-like helical domain-containing protein 3 isoform X8

    Conserved Domains (1) summary
    pfam08427
    Location:441599
    DUF1741; Domain of unknown function (DUF1741)
  9. XM_047425734.1XP_047281690.1  armadillo-like helical domain-containing protein 3 isoform X8

  10. XM_011540151.4XP_011538453.1  armadillo-like helical domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011538453.1

    UniProtKB/Swiss-Prot
    Q5T2E6, Q9H8Z9
    Conserved Domains (1) summary
    pfam08427
    Location:441669
    DUF1741; Domain of unknown function (DUF1741)
  11. XM_011540156.3XP_011538458.1  armadillo-like helical domain-containing protein 3 isoform X14

    Conserved Domains (1) summary
    pfam08427
    Location:267495
    DUF1741; Domain of unknown function (DUF1741)
  12. XM_017016635.2XP_016872124.1  armadillo-like helical domain-containing protein 3 isoform X3

    Conserved Domains (1) summary
    pfam08427
    Location:441620
    DUF1741; Domain of unknown function (DUF1741)
  13. XM_047425733.1XP_047281689.1  armadillo-like helical domain-containing protein 3 isoform X6

  14. XM_017016636.3XP_016872125.1  armadillo-like helical domain-containing protein 3 isoform X6

    Conserved Domains (1) summary
    pfam08427
    Location:441620
    DUF1741; Domain of unknown function (DUF1741)
  15. XM_047425740.1XP_047281696.1  armadillo-like helical domain-containing protein 3 isoform X13

  16. XM_047425738.1XP_047281694.1  armadillo-like helical domain-containing protein 3 isoform X12

RNA

  1. XR_001747199.2 RNA Sequence

  2. XR_007061987.1 RNA Sequence

  3. XR_007061988.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    102729087..102941185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)