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sod3b superoxide dismutase 3, extracellular b [ Danio rerio (zebrafish) ]

Gene ID: 794006, updated on 16-Apr-2023

Summary

Official Symbol
sod3bprovided by ZNC
Official Full Name
superoxide dismutase 3, extracellular bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8743
See related
Ensembl:ENSDARG00000079183 AllianceGenome:ZFIN:ZDB-GENE-030131-8743
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sod3; fb05f10; wu:fb05f10; si:dkey-117m1.6
Summary
Predicted to enable copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Predicted to act upstream of or within superoxide metabolic process. Is expressed in digestive system; female organism; and male organism. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See sod3b in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (39990417..39992048)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39272467..39273975)
103 previous assembly Zv9 (GCF_000002035.4) 1 NC_007112.5 (40353042..40354602)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene storkhead box 2a Neighboring gene uncharacterized LOC110439845 Neighboring gene inhibitor of growth family, member 2 Neighboring gene aryl hydrocarbon receptor interacting protein Neighboring gene cyclin dependent kinase 2 associated protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
 
enables heparin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables superoxide dismutase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables superoxide dismutase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables superoxide dismutase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in removal of superoxide radicals IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within removal of superoxide radicals IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within superoxide metabolic process IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]
XP_001332758.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    39990417..39992048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001332722.8XP_001332758.1  extracellular superoxide dismutase [Cu-Zn]

    UniProtKB/TrEMBL
    A0A8M1PYQ3, E9QIM2
    Related
    ENSDARP00000097881.2, ENSDART00000112150.4
    Conserved Domains (1) summary
    pfam00080
    Location:55185
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)