U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR4C5 olfactory receptor family 4 subfamily C member 5 [ Homo sapiens (human) ]

Gene ID: 79346, updated on 22-Sep-2022

Summary

Official Symbol
OR4C5provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily C member 5provided by HGNC
Primary source
HGNC:HGNC:14702
See related
Ensembl:ENSG00000176540 AllianceGenome:HGNC:14702
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR4C5P; OR4C5Q
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR4C5 in Genome Data Viewer
Location:
11p11.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (48365485..48366465, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (48535073..48536053, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (48387037..48388017, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily C member 3 Neighboring gene olfactory receptor family 4 subfamily C member 4 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 2 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 10 pseudogene

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 4C5
Names
olfactory receptor OR11-99
olfactory receptor, family 4, subfamily C, member 5 pseudogene
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348223.2NP_001335152.1  olfactory receptor 4C5

    Status: VALIDATED

    Source sequence(s)
    AC023080
    Consensus CDS
    CCDS86201.1
    UniProtKB/Swiss-Prot
    Q6IFB2, Q8NGB2
    Related
    ENSP00000321338.3, ENST00000319813.3
    Conserved Domains (1) summary
    cd15939
    Location:46304
    7tmA_OR4A-like; olfactory receptor 4A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    48365485..48366465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    48535073..48536053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_002247.2: Suppressed sequence

    Description
    NG_002247.2: This RefSeq was removed because it is now thought that this gene does encode a protein.