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OR51B2 olfactory receptor family 51 subfamily B member 2 [ Homo sapiens (human) ]

Gene ID: 79345, updated on 1-Jun-2020

Summary

Official Symbol
OR51B2provided by HGNC
Official Full Name
olfactory receptor family 51 subfamily B member 2provided by HGNC
Primary source
HGNC:HGNC:14703
See related
Ensembl:ENSG00000279012
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR51B1P; HOR5'Beta3
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
Orthologs

Genomic context

See OR51B2 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (5323298..5324352, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5344528..5345582, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene beta-globin locus control region Neighboring gene olfactory receptor family 51 subfamily B member 4 Neighboring gene olfactory receptor family 51 subfamily B member 3 pseudogene Neighboring gene olfactory receptor family 51 subfamily B member 8 pseudogene Neighboring gene olfactory receptor family 51 subfamily B member 5 Neighboring gene olfactory receptor family 51 subfamily B member 6

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 51B2
Names
odorant receptor HOR5'beta3
olfactory receptor 51B1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033180.4NP_149420.4  olfactory receptor 51B2

    See identical proteins and their annotated locations for NP_149420.4

    Status: VALIDATED

    Source sequence(s)
    AC104389, BC117461
    UniProtKB/Swiss-Prot
    Q9Y5P1
    UniProtKB/TrEMBL
    A0A126GWB2, Q17R53
    Related
    ENSP00000485407.1, ENST00000624187.1
    Conserved Domains (2) summary
    pfam00001
    Location:39290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29306
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    5323298..5324352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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