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OR11H2 olfactory receptor family 11 subfamily H member 2 [ Homo sapiens (human) ]

Gene ID: 79334, updated on 26-Oct-2022

Summary

Official Symbol
OR11H2provided by HGNC
Official Full Name
olfactory receptor family 11 subfamily H member 2provided by HGNC
Primary source
HGNC:HGNC:14716
See related
Ensembl:ENSG00000258453 AllianceGenome:HGNC:14716
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11H13; OR11H2P; OR11H8P; C14orf15
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

See OR11H2 in Genome Data Viewer
Location:
14q11.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (19712936..19713883, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (13912770..13913717, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20181095..20182042, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene fatty acyl-CoA reductase 2 pseudogene Neighboring gene ubiquitin specific peptidase 10 pseudogene 1 Neighboring gene ARHGAP42 pseudogene 4 Neighboring gene olfactory receptor family 11 subfamily K member 2 pseudogene Neighboring gene olfactory receptor family 4 subfamily Q member 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 11H2
Names
olfactory receptor OR14-1
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001197287.2NP_001184216.2  olfactory receptor 11H2

    Status: VALIDATED

    Source sequence(s)
    AL512310
    Consensus CDS
    CCDS76655.2
    UniProtKB/TrEMBL
    A0A2C9F2Y1
    Related
    ENSP00000485150.2, ENST00000556246.3
    Conserved Domains (1) summary
    cd15913
    Location:29298
    7tmA_OR11G-like; olfactory receptor OR11G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    19712936..19713883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    13912770..13913717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_002568.2: Suppressed sequence

    Description
    NG_002568.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
  2. NG_004141.3: Suppressed sequence

    Description
    NG_004141.3: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.