edf1 endothelial differentiation-related factor 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: edf1provided by ZNC
Official Full Name: endothelial differentiation-related factor 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1710
See related: Ensembl:ENSDARG00000009950 AllianceGenome:ZFIN:ZDB-GENE-040426-1710
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73192; zgc:86829
Summary: Predicted to enable DNA binding activity. Predicted to be active in nucleus. Orthologous to human EDF1 (endothelial differentiation related factor 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	5	NC_133180.1 (70325332..70333749)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (64397643..64406058)

Chromosome 5 - NC_133180.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi37a12.x1 (e-PCR)
- UniSTS:204573

fk33b04.y1 (e-PCR)
- UniSTS:200835

fe06b03.x1 (e-PCR)
- UniSTS:196011

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: endothelial differentiation-related factor 1 homolog

Names: EDF-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200745.1 → NP_957039.1 endothelial differentiation-related factor 1 homolog

See identical proteins and their annotated locations for NP_957039.1

Status: PROVISIONAL

Source sequence(s)

BC059541

UniProtKB/Swiss-Prot

Q6PBY3

UniProtKB/TrEMBL

A5PN46

Related

ENSDARP00000026769.5, ENSDART00000015940.7

Conserved Domains (2) summary

smart00530
Location:80 → 132

HTH_XRE; Helix-turn-helix XRE-family like proteins

pfam08523
Location:4 → 71

MBF1; Multiprotein bridging factor 1