Format

Send to:

Choose Destination

ZNF576 zinc finger protein 576 [ Homo sapiens (human) ]

Gene ID: 79177, updated on 23-Nov-2021

Summary

Official Symbol
ZNF576provided by HGNC
Official Full Name
zinc finger protein 576provided by HGNC
Primary source
HGNC:HGNC:28357
See related
Ensembl:ENSG00000124444
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in prostate (RPKM 1.5), fat (RPKM 1.4) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZNF576 in Genome Data Viewer
Location:
19q13.31
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (43596392..43601157)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (44100544..44105309)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene phospholipase A2 inhibitor and LY6/PLAUR domain containing Neighboring gene immunity related GTPase Q Neighboring gene zinc finger protein 428 Neighboring gene serine/arginine repetitive matrix 5 Neighboring gene uncharacterized LOC105372411 Neighboring gene cell adhesion molecule 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: SRRM5

Homology

Clone Names

  • MGC2508, FLJ22700, FLJ56397

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145347.2NP_001138819.1  zinc finger protein 576

    See identical proteins and their annotated locations for NP_001138819.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC006276, BC002981, BP358040
    Consensus CDS
    CCDS12625.1
    UniProtKB/Swiss-Prot
    Q9H609
    UniProtKB/TrEMBL
    A0A024R0T0
    Related
    ENSP00000337852.4, ENST00000336564.5
    Conserved Domains (2) summary
    sd00017
    Location:7393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:112134
    zf-C2H2; Zinc finger, C2H2 type
  2. NM_024327.2NP_077303.1  zinc finger protein 576

    See identical proteins and their annotated locations for NP_077303.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC006276, AK026353
    Consensus CDS
    CCDS12625.1
    UniProtKB/Swiss-Prot
    Q9H609
    UniProtKB/TrEMBL
    A0A024R0T0
    Related
    ENSP00000375827.2, ENST00000391965.6
    Conserved Domains (2) summary
    sd00017
    Location:7393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:112134
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    43596392..43601157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center