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BAG6 BAG cochaperone 6 [ Homo sapiens (human) ]

Gene ID: 7917, updated on 5-Sep-2021

Summary

Official Symbol
BAG6provided by HGNC
Official Full Name
BAG cochaperone 6provided by HGNC
Primary source
HGNC:HGNC:13919
See related
Ensembl:ENSG00000204463 MIM:142590
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
G3; BAT3; BAG-6; D6S52E
Summary
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression
Broad expression in testis (RPKM 77.2), spleen (RPKM 25.1) and 25 other tissues See more
Orthologs
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Genomic context

See BAG6 in Genome Data Viewer
Location:
6p21.33
Exon count:
30
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (31639028..31660900, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (31606805..31620438, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene proline rich coiled-coil 2A Neighboring gene small nucleolar RNA, H/ACA box 38 Neighboring gene microRNA 6832 Neighboring gene apolipoprotein M Neighboring gene chromosome 6 open reading frame 47 Neighboring gene G-patch domain and ankyrin repeats 1 Neighboring gene casein kinase 2 beta Neighboring gene lymphocyte antigen 6 family member G5B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
A comprehensive family-based replication study of schizophrenia genes.
GeneReviews: Not available
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
GeneReviews: Not available
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
GeneReviews: Not available
Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis.
GeneReviews: Not available
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
GeneReviews: Not available
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
GeneReviews: Not available

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of BCL2-associated athanogene 6 (BAG6) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif interacts with BAG6; predicted interaction to be relevant to gene regulation and/or location PubMed
vif HIV-1 Vif is identified to have a physical interaction with BCL2-associated athanogene 6 (BAG6; BAT3) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables Hsp70 protein binding IEA
Inferred from Electronic Annotation
more info
 
enables misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables misfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables polyubiquitin modification-dependent protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables proteasome binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin-specific protease binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in ER-associated misfolded protein catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in brain development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in endoplasmic reticulum stress-induced pre-emptive quality control IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in immune response-activating cell surface receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in internal peptidyl-lysine acetylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in kidney development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in lung development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in maintenance of unfolded protein involved in ERAD pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in natural killer cell activation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of proteolysis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of ERAD pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proteasomal protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to cytosolic proteasome complex involved in ERAD pathway NAS
Non-traceable Author Statement
more info
PubMed 
involved_in protein stabilization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of embryonic development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in spermatogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in synaptonemal complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in tail-anchored membrane protein insertion into ER membrane IDA
Inferred from Direct Assay
more info
PubMed 
involved_in ubiquitin-dependent ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ubiquitin-dependent ERAD pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in ubiquitin-dependent ERAD pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of BAT3 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of BAT3 complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
located_in membrane HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
large proline-rich protein BAG6
Names
BAG family molecular chaperone regulator 6
BCL2 associated athanogene 6
HLA-B-associated transcript 3
large proline-rich protein BAT3
protein G3
protein Scythe
scythe

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098534.2NP_001092004.1  large proline-rich protein BAG6 isoform 2

    See identical proteins and their annotated locations for NP_001092004.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and utilizes an alternative in-frame splice site in the 5' coding region, compared to variant 1. Variants 2, 3, and 4 encode the same isoform (b), which is 6 aa shorter than isoform a.
    Source sequence(s)
    BC003133, BF515863, BX647244, CX758454, DB492350
    Consensus CDS
    CCDS4709.1
    UniProtKB/Swiss-Prot
    P46379
    UniProtKB/TrEMBL
    A0A1U9X7A6
    Related
    ENSP00000365143.4, ENST00000375976.8
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  2. NM_001199697.2NP_001186626.1  large proline-rich protein BAG6 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and lacks three alternate in-frame segments compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AK302695, AK304879, AU134255, BU628873
    Consensus CDS
    CCDS56414.1
    UniProtKB/Swiss-Prot
    P46379
    Related
    ENSP00000402856.2, ENST00000439687.6
    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    smart00213
    Location:1787
    UBQ; Ubiquitin homologues
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  3. NM_001199698.2NP_001186627.1  large proline-rich protein BAG6 isoform 4

    See identical proteins and their annotated locations for NP_001186627.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (d) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AK302695, AK304879, AU134255, BC003133, BU628873
    Consensus CDS
    CCDS56415.1
    UniProtKB/Swiss-Prot
    P46379
    Related
    ENSP00000354875.6, ENST00000362049.10
    Conserved Domains (3) summary
    PRK07764
    Location:8991077
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  4. NM_001387940.1NP_001374869.1  large proline-rich protein BAG6 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991077
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  5. NM_001387942.1NP_001374871.1  large proline-rich protein BAG6 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8801058
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  6. NM_001387943.1NP_001374872.1  large proline-rich protein BAG6 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (2) summary
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  7. NM_001387944.1NP_001374873.1  large proline-rich protein BAG6 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8811059
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  8. NM_001387946.1NP_001374875.1  large proline-rich protein BAG6 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (2) summary
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  9. NM_001387949.1NP_001374878.1  large proline-rich protein BAG6 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (2) summary
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  10. NM_001387951.1NP_001374880.1  large proline-rich protein BAG6 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (2) summary
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  11. NM_001387954.1NP_001374883.1  large proline-rich protein BAG6 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351113
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  12. NM_001387955.1NP_001374884.1  large proline-rich protein BAG6 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8981076
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  13. NM_001387956.1NP_001374885.1  large proline-rich protein BAG6 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991077
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  14. NM_001387958.1NP_001374887.1  large proline-rich protein BAG6 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9171095
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  15. NM_001387961.1NP_001374890.1  large proline-rich protein BAG6 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  16. NM_001387963.1NP_001374892.1  large proline-rich protein BAG6 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8801071
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  17. NM_001387964.1NP_001374893.1  large proline-rich protein BAG6 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8811072
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  18. NM_001387965.1NP_001374894.1  large proline-rich protein BAG6 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351113
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  19. NM_001387982.1NP_001374911.1  large proline-rich protein BAG6 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8811072
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  20. NM_001387983.1NP_001374912.1  large proline-rich protein BAG6 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341112
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  21. NM_001387984.1NP_001374913.1  large proline-rich protein BAG6 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351113
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  22. NM_001387985.1NP_001374914.1  large proline-rich protein BAG6 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (4) summary
    PHA03247
    Location:374577
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:9441122
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  23. NM_001387986.1NP_001374915.1  large proline-rich protein BAG6 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  24. NM_001387987.1NP_001374916.1  large proline-rich protein BAG6 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8981089
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  25. NM_001387988.1NP_001374917.1  large proline-rich protein BAG6 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341125
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  26. NM_001387989.1NP_001374918.1  large proline-rich protein BAG6 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351126
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  27. NM_001387990.1NP_001374919.1  large proline-rich protein BAG6 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8981089
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  28. NM_001387991.1NP_001374920.1  large proline-rich protein BAG6 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9171108
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  29. NM_001387992.1NP_001374921.1  large proline-rich protein BAG6 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9171108
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  30. NM_001387993.1NP_001374922.1  large proline-rich protein BAG6 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341125
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  31. NM_001387994.1NP_001374923.1  large proline-rich protein BAG6 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Related
    ENSP00000502941.1, ENST00000676615.1
    Conserved Domains (3) summary
    PRK07764
    Location:9351126
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  32. NM_001387995.1NP_001374924.1  large proline-rich protein BAG6 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341125
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  33. NM_001387996.1NP_001374925.1  large proline-rich protein BAG6 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351126
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  34. NM_001387997.1NP_001374926.1  large proline-rich protein BAG6 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8811059
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  35. NM_001387998.1NP_001374927.1  large proline-rich protein BAG6 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8981076
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  36. NM_001387999.1NP_001374928.1  large proline-rich protein BAG6 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991077
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  37. NM_001388000.1NP_001374929.1  large proline-rich protein BAG6 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (2) summary
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  38. NM_001388001.1NP_001374930.1  large proline-rich protein BAG6 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991077
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  39. NM_001388002.1NP_001374931.1  large proline-rich protein BAG6 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8721063
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  40. NM_001388003.1NP_001374932.1  large proline-rich protein BAG6 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8731064
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  41. NM_001388004.1NP_001374933.1  large proline-rich protein BAG6 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8811072
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  42. NM_001388005.1NP_001374934.1  large proline-rich protein BAG6 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341112
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  43. NM_001388006.1NP_001374935.1  large proline-rich protein BAG6 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351113
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  44. NM_001388007.1NP_001374936.1  large proline-rich protein BAG6 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8981089
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  45. NM_001388008.1NP_001374937.1  large proline-rich protein BAG6 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (4) summary
    PHA03247
    Location:374529
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:9071098
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  46. NM_001388009.1NP_001374938.1  large proline-rich protein BAG6 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (4) summary
    PHA03247
    Location:374541
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:9081099
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  47. NM_001388010.1NP_001374939.1  large proline-rich protein BAG6 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341125
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  48. NM_001388011.1NP_001374940.1  large proline-rich protein BAG6 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351126
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  49. NM_001388012.1NP_001374941.1  large proline-rich protein BAG6 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (4) summary
    PHA03247
    Location:374577
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:9441135
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  50. NM_001388013.1NP_001374942.1  large proline-rich protein BAG6 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (2) summary
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  51. NM_001388014.1NP_001374943.1  large proline-rich protein BAG6 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991077
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  52. NM_001388015.1NP_001374944.1  large proline-rich protein BAG6 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  53. NM_001388016.1NP_001374945.1  large proline-rich protein BAG6 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341112
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  54. NM_001388017.1NP_001374946.1  large proline-rich protein BAG6 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  55. NM_001388018.1NP_001374947.1  large proline-rich protein BAG6 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  56. NM_001388019.1NP_001374948.1  large proline-rich protein BAG6 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9341125
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  57. NM_001388020.1NP_001374949.1  large proline-rich protein BAG6 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL662801
    Conserved Domains (3) summary
    PRK07764
    Location:9351126
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  58. NM_080702.3NP_542433.1  large proline-rich protein BAG6 isoform 2

    See identical proteins and their annotated locations for NP_542433.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and utilizes an alternative in-frame splice site in the 5' coding region, compared to variant 1. Variants 2, 3, and 4 encode the same isoform (b), which is 6 aa shorter than isoform a.
    Source sequence(s)
    BC003133, BF515863, BX384328, DB454794
    Consensus CDS
    CCDS4709.1
    UniProtKB/Swiss-Prot
    P46379
    UniProtKB/TrEMBL
    A0A1U9X7A6
    Related
    ENSP00000211379.5, ENST00000211379.9
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  59. NM_080703.3NP_542434.1  large proline-rich protein BAG6 isoform 2

    See identical proteins and their annotated locations for NP_542434.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) utilizes an alternative in-frame splice site in the 5' coding region, compared to variant 1. Variants 2, 3, and 4 encode the same isoform (b), which is 6 aa shorter than isoform a.
    Source sequence(s)
    BC003133, BF515863, BX384328, DB459208
    Consensus CDS
    CCDS4709.1
    UniProtKB/Swiss-Prot
    P46379
    UniProtKB/TrEMBL
    A0A1U9X7A6
    Conserved Domains (3) summary
    PRK07764
    Location:8991090
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    31639028..31660900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017011297.2XP_016866786.1  large proline-rich protein BAG6 isoform X14

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    smart00213
    Location:1787
    UBQ; Ubiquitin homologues
    pfam12057
    Location:252368
    DUF3538; Domain of unknown function (DUF3538)
  2. XM_017011298.2XP_016866787.1  large proline-rich protein BAG6 isoform X17

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    smart00213
    Location:1787
    UBQ; Ubiquitin homologues
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  3. XM_017011296.2XP_016866785.1  large proline-rich protein BAG6 isoform X16

    Conserved Domains (3) summary
    PRK07764
    Location:8981076
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  4. XM_017011295.2XP_016866784.1  large proline-rich protein BAG6 isoform X15

  5. XM_017011290.2XP_016866779.1  large proline-rich protein BAG6 isoform X8

  6. XM_017011291.2XP_016866780.1  large proline-rich protein BAG6 isoform X9

  7. XM_017011275.2XP_016866764.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  8. XM_017011279.2XP_016866768.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  9. XM_024446545.1XP_024302313.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  10. XM_017011278.2XP_016866767.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  11. XM_017011285.2XP_016866774.1  large proline-rich protein BAG6 isoform X5

  12. XM_017011294.2XP_016866783.1  large proline-rich protein BAG6 isoform X13

    Related
    ENSP00000365131.6, ENST00000375964.11
    Conserved Domains (3) summary
    PRK07764
    Location:8731064
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  13. XM_011514892.3XP_011513194.1  large proline-rich protein BAG6 isoform X3

    See identical proteins and their annotated locations for XP_011513194.1

    Related
    ENSP00000504005.1, ENST00000676571.1
    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    smart00213
    Location:1787
    UBQ; Ubiquitin homologues
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  14. XM_017011289.2XP_016866778.1  large proline-rich protein BAG6 isoform X7

    Conserved Domains (4) summary
    PHA03247
    Location:374541
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:9081099
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  15. XM_017011284.2XP_016866773.1  large proline-rich protein BAG6 isoform X4

    Conserved Domains (4) summary
    PHA03247
    Location:374577
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:9441135
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
  16. XM_017011283.2XP_016866772.1  large proline-rich protein BAG6 isoform X2

  17. XM_017011276.2XP_016866765.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  18. XM_017011286.2XP_016866775.1  large proline-rich protein BAG6 isoform X5

  19. XM_017011277.2XP_016866766.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  20. XM_024446546.1XP_024302314.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  21. XM_017011282.2XP_016866771.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  22. XM_017011281.2XP_016866770.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  23. XM_017011280.2XP_016866769.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    cd01809
    Location:1787
    Scythe_N; Ubiquitin-like domain of Scythe protein
    pfam12057
    Location:270386
    DUF3538; Domain of unknown function (DUF3538)
    cl26386
    Location:9551146
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    3116310..3129951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_3

Genomic

  1. NT_167245.2 Reference GRCh38.p13 ALT_REF_LOCI_3

    Range
    2886791..2900432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_4

Genomic

  1. NT_167246.2 Reference GRCh38.p13 ALT_REF_LOCI_4

    Range
    2944068..2957707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_5

Genomic

  1. NT_167247.2 Reference GRCh38.p13 ALT_REF_LOCI_5

    Range
    2980907..2994533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_6

Genomic

  1. NT_167248.2 Reference GRCh38.p13 ALT_REF_LOCI_6

    Range
    2894841..2908480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_7

Genomic

  1. NT_167249.2 Reference GRCh38.p13 ALT_REF_LOCI_7

    Range
    2938304..2951939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_004639.3: Suppressed sequence

    Description
    NM_004639.3: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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