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GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 [ Homo sapiens (human) ]

Gene ID: 79153, updated on 1-Jun-2020

Summary

Official Symbol
GDPD3provided by HGNC
Official Full Name
glycerophosphodiester phosphodiesterase domain containing 3provided by HGNC
Primary source
HGNC:HGNC:28638
See related
Ensembl:ENSG00000102886 MIM:616318
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GDE7
Expression
Broad expression in esophagus (RPKM 15.4), colon (RPKM 11.2) and 22 other tissues See more
Orthologs

Genomic context

See GDPD3 in Genome Data Viewer
Location:
16p11.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (30104810..30113537, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (30115977..30125264, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928595 Neighboring gene T-box transcription factor 6 Neighboring gene yippee like 3 Neighboring gene mitogen-activated protein kinase 3 Neighboring gene uncharacterized LOC107984834 Neighboring gene coronin 1A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC4171, FLJ22603

Gene Ontology Provided by GOA

Function Evidence Code Pubs
lysophospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
glycerophospholipid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylcholine catabolic process IEA
Inferred from Electronic Annotation
more info
 
phospholipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular exosome HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
lysophospholipase D GDPD3
Names
glycerophosphodiester phosphodiesterase 7
glycerophosphodiester phosphodiesterase domain-containing protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024307.3NP_077283.2  lysophospholipase D GDPD3

    See identical proteins and their annotated locations for NP_077283.2

    Status: VALIDATED

    Source sequence(s)
    BC002714
    Consensus CDS
    CCDS10671.2
    UniProtKB/Swiss-Prot
    Q7L5L3
    Related
    ENSP00000384363.3, ENST00000406256.8
    Conserved Domains (2) summary
    cd08612
    Location:13310
    GDPD_GDE4; Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins
    pfam03009
    Location:44301
    GDPD; Glycerophosphoryl diester phosphodiesterase family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    30104810..30113537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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