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ZSCAN5A zinc finger and SCAN domain containing 5A [ Homo sapiens (human) ]

Gene ID: 79149, updated on 13-Mar-2020

Summary

Official Symbol
ZSCAN5Aprovided by HGNC
Official Full Name
zinc finger and SCAN domain containing 5Aprovided by HGNC
Primary source
HGNC:HGNC:23710
See related
Ensembl:ENSG00000131848
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF495; ZSCAN5
Expression
Broad expression in testis (RPKM 6.0), kidney (RPKM 0.7) and 21 other tissues See more
Orthologs

Genomic context

See ZSCAN5A in Genome Data Viewer
Location:
19q13.43
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (56219670..56368383, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56732672..56826208, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger and SCAN domain containing 5C Neighboring gene ribosomal protein L13 pseudogene 13 Neighboring gene zinc finger and SCAN domain containing 5D pseudogene Neighboring gene uncharacterized LOC105372470 Neighboring gene epididymal protein 13 Neighboring gene uncharacterized LOC112268243 Neighboring gene uncharacterized LOC105372468 Neighboring gene glycerol-3-phosphate dehydrogenase 2 (mitochondrial) pseudogene Neighboring gene vomeronasal 2 receptor 17, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 1 pseudogene Neighboring gene vomeronasal 2 receptor 18 pseudogene Neighboring gene Sharpr-MPRA regulatory region 13801 Neighboring gene zinc finger protein 542, pseudogene Neighboring gene SLC25A36 pseudogene 1 Neighboring gene zinc finger protein 582 Neighboring gene ZNF582 antisense RNA 1 (head to head)

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC4161

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 5A
Names
zinc finger and SCAN domain containing 5
zinc finger protein 495

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322061.2NP_001308990.1  zinc finger and SCAN domain-containing protein 5A isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variant 2 both encode isoform a.
    Source sequence(s)
    AC006116, AC011506
    Conserved Domains (4) summary
    cd07936
    Location:93177
    SCAN; SCAN oligomerization domain
    COG5048
    Location:391544
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:466486
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:506531
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001322062.1NP_001308991.1  zinc finger and SCAN domain-containing protein 5A isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) and variant 1 both encode isoform a.
    Source sequence(s)
    AC011506, AI699820, AK098700, DB028988
    UniProtKB/Swiss-Prot
    Q9BUG6
    Conserved Domains (4) summary
    cd07936
    Location:93177
    SCAN; SCAN oligomerization domain
    COG5048
    Location:391544
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:466486
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:506531
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001322064.2NP_001308993.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), along with variants 3, 5-8, and 10-11, encodes isoform b.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Related
    ENSP00000375593.1, ENST00000391713.5
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001322065.2NP_001308994.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), along with variants 3-4, 6-8, and 10-11, encodes isoform b.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  5. NM_001322066.1NP_001308995.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), along with variants 3-5, 7-8, and 10-11, encodes isoform b.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  6. NM_001322067.1NP_001308996.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), along with variants 3-6, 8, and 10-11, encodes isoform b.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  7. NM_001322068.1NP_001308997.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), along with variants 3-7 and 10-11, encodes isoform b.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  8. NM_001322070.1NP_001308999.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), along with variants 3-8 and 11, encodes isoform b.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  9. NM_001322072.1NP_001309001.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), along with variants 3-8 and 10, encodes isoform b.
    Source sequence(s)
    AC011506, AI699820, BC043232
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Related
    ENSP00000467631.1, ENST00000587340.5
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  10. NM_001322073.2NP_001309002.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), along with variants 13-15, encodes isoform c.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Related
    ENSP00000467238.1, ENST00000592355.5
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  11. NM_001322074.2NP_001309003.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13), along with variants 12 and 14-15, encodes isoform c.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  12. NM_001322075.1NP_001309004.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14), along with variants 12-13 and 15, encodes isoform c.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  13. NM_001322076.1NP_001309005.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15), along with variants 12-14, encodes isoform c.
    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  14. NM_001322077.2NP_001309006.1  zinc finger and SCAN domain-containing protein 5A isoform d

    Status: VALIDATED

    Source sequence(s)
    AC011506, AI699820, AK301873, BC043232
    UniProtKB/Swiss-Prot
    Q9BUG6
    Related
    ENSP00000466445.1, ENST00000587492.5
    Conserved Domains (3) summary
    COG5048
    Location:222375
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:297317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:337362
    zf-H2C2_2; Zinc-finger double domain
  15. NM_001322078.2NP_001309007.1  zinc finger and SCAN domain-containing protein 5A isoform e

    Status: VALIDATED

    Source sequence(s)
    AC011506, AI699820, AK301873, BC043232, BI916125
    UniProtKB/Swiss-Prot
    Q9BUG6
    Conserved Domains (3) summary
    COG5048
    Location:209362
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:284304
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:324349
    zf-H2C2_2; Zinc-finger double domain
  16. NM_024303.2NP_077279.1  zinc finger and SCAN domain-containing protein 5A isoform b

    See identical proteins and their annotated locations for NP_077279.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), along with variants 4-8 and 10-11, encodes isoform b.
    Source sequence(s)
    AC011506, AI699820, AK098700, BC002636, DB028988
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    Q9BUG6
    UniProtKB/TrEMBL
    A0A024R4S6
    Conserved Domains (5) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam03546
    Location:213355
    Treacle; Treacher Collins syndrome protein Treacle
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    56219670..56368383 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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