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ZSCAN5A zinc finger and SCAN domain containing 5A [ Homo sapiens (human) ]

Gene ID: 79149, updated on 11-Apr-2024

Summary

Official Symbol
ZSCAN5Aprovided by HGNC
Official Full Name
zinc finger and SCAN domain containing 5Aprovided by HGNC
Primary source
HGNC:HGNC:23710
See related
Ensembl:ENSG00000131848 AllianceGenome:HGNC:23710
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF495; ZSCAN5
Summary
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 6.0), kidney (RPKM 0.7) and 21 other tissues See more
Orthologs
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Genomic context

See ZSCAN5A in Genome Data Viewer
Location:
19q13.43
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (56221303..56368278, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (59320082..59462670, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56732672..56879647, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_51953 Neighboring gene zinc finger and SCAN domain containing 5C Neighboring gene ribosomal protein L13 pseudogene 13 Neighboring gene uncharacterized LOC124904774 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr19:56747404-56748603 Neighboring gene zinc finger and SCAN domain containing 5D pseudogene Neighboring gene uncharacterized LOC124904775 Neighboring gene uncharacterized LOC124900420 Neighboring gene epididymal protein 13 Neighboring gene uncharacterized LOC105372468 Neighboring gene ZSCAN5A antisense RNA 1 Neighboring gene glycerol-3-phosphate dehydrogenase 2 (mitochondrial) pseudogene Neighboring gene vomeronasal 2 receptor 17, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 1 pseudogene Neighboring gene vomeronasal 2 receptor 18 pseudogene Neighboring gene Sharpr-MPRA regulatory region 13801 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15118 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56888366-56889565 Neighboring gene zinc finger protein 542, pseudogene Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56895030-56896229 Neighboring gene SLC25A36 pseudogene 1 Neighboring gene zinc finger protein 582 Neighboring gene ZNF582 divergent transcript

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 5A
Names
zinc finger and SCAN domain containing 5
zinc finger protein 495

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322061.4NP_001308990.2  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001322062.2NP_001308991.2  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Related
    ENSP00000467238.1, ENST00000592355.5
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001322064.3NP_001308993.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Related
    ENSP00000507065.1, ENST00000683990.1
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001322065.3NP_001308994.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  5. NM_001322066.2NP_001308995.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  6. NM_001322067.2NP_001308996.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  7. NM_001322068.2NP_001308997.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  8. NM_001322070.2NP_001308999.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  9. NM_001322072.3NP_001309001.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Related
    ENSP00000467631.1, ENST00000587340.5
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  10. NM_001322073.2NP_001309002.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  11. NM_001322074.2NP_001309003.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  12. NM_001322075.2NP_001309004.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  13. NM_001322076.2NP_001309005.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  14. NM_001322077.3NP_001309006.1  zinc finger and SCAN domain-containing protein 5A isoform d

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    UniProtKB/Swiss-Prot
    Q9BUG6
    Related
    ENSP00000466445.1, ENST00000587492.5
    Conserved Domains (3) summary
    COG5048
    Location:222375
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:297317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:337362
    zf-H2C2_2; Zinc-finger double domain
  15. NM_001322078.3NP_001309007.1  zinc finger and SCAN domain-containing protein 5A isoform e

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    UniProtKB/Swiss-Prot
    Q9BUG6
    Conserved Domains (3) summary
    COG5048
    Location:209362
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:284304
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:324349
    zf-H2C2_2; Zinc-finger double domain
  16. NM_001387853.1NP_001374782.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  17. NM_001387854.1NP_001374783.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  18. NM_001387855.1NP_001374784.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  19. NM_001387856.1NP_001374785.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  20. NM_001387857.1NP_001374786.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  21. NM_001387858.1NP_001374787.1  zinc finger and SCAN domain-containing protein 5A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS82403.1
    UniProtKB/TrEMBL
    A0A0C4DGQ1
    Conserved Domains (4) summary
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:338491
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453478
    zf-H2C2_2; Zinc-finger double domain
  22. NM_001387859.1NP_001374788.1  zinc finger and SCAN domain-containing protein 5A isoform b

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain
  23. NM_024303.4NP_077279.1  zinc finger and SCAN domain-containing protein 5A isoform b

    See identical proteins and their annotated locations for NP_077279.1

    Status: VALIDATED

    Source sequence(s)
    AC011506
    Consensus CDS
    CCDS12941.1
    UniProtKB/Swiss-Prot
    B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
    Related
    ENSP00000375593.1, ENST00000391713.5
    Conserved Domains (5) summary
    TIGR00934
    Location:117328
    2a38euk; potassium uptake protein, Trk family
    cd07936
    Location:40124
    SCAN; SCAN oligomerization domain
    COG5048
    Location:339492
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:414434
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:454479
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    56221303..56368278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    59320082..59462670 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)