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prdx2 peroxiredoxin 2 [ Danio rerio (zebrafish) ]

Gene ID: 791455, updated on 14-Feb-2019

Summary

Official Symbol
prdx2provided by ZNC
Official Full Name
peroxiredoxin 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030326-2
See related
Ensembl:ENSDARG00000025350
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
cb58; prdx1; zgc:92891; wu:fq19b09
Orthologs

Genomic context

See prdx2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (51721851..51729866)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (51087487..51095502)
103 previous assembly Zv9 (GCF_000002035.4) 1 NC_007112.5 (52215803..52223818)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein polypeptide B2 Neighboring gene ribonuclease H2, subunit A Neighboring gene JunB proto-oncogene, AP-1 transcription factor subunit a Neighboring gene si:ch211-145g9.7

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Homology

Clone Names

  • MGC92891

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
antioxidant activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
 
thioredoxin peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cell redox homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 
hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
leukocyte activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
removal of superoxide radicals IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
peroxiredoxin-2
Names
peroxiredoxin 1
NP_001002468.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002468.2NP_001002468.1  peroxiredoxin-2

    See identical proteins and their annotated locations for NP_001002468.1

    Status: VALIDATED

    Source sequence(s)
    EB860866, EH486177, EH575743
    UniProtKB/TrEMBL
    Q6DGJ6
    Related
    ENSDARP00000040396.4, ENSDART00000040397.5
    Conserved Domains (2) summary
    PTZ00253
    Location:1195
    PTZ00253; tryparedoxin peroxidase; Provisional
    cd03015
    Location:8179
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    51721851..51729866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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