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PPDPF pancreatic progenitor cell differentiation and proliferation factor [ Homo sapiens (human) ]

Gene ID: 79144, updated on 29-Mar-2018
Official Symbol
PPDPFprovided by HGNC
Official Full Name
pancreatic progenitor cell differentiation and proliferation factorprovided by HGNC
Primary source
HGNC:HGNC:16142
See related
Ensembl:ENSG00000125534 Vega:OTTHUMG00000032978
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
exdpf; C20orf149; dJ697K14.9
Expression
Broad expression in colon (RPKM 131.3), stomach (RPKM 115.2) and 25 other tissues See more
Orthologs
Location:
20q13.33
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 20 NC_000020.11 (63520741..63522171)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (62151426..62153524)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372725 Neighboring gene uncharacterized LOC102723814 Neighboring gene protein tyrosine kinase 6 Neighboring gene src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

NHGRI GWAS Catalog

Description
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
NHGRI GWA Catalog

Markers

Homology

Clone Names

  • MGC2479, FLJ21046

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell fate specification IBA
Inferred from Biological aspect of Ancestor
more info
 
exocrine pancreas development IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
pancreatic progenitor cell differentiation and proliferation factor
Names
exocrine differentiation and proliferation factor
pancreatic progenitor cell differentiation and proliferation factor homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001353423.1NP_001340352.1  pancreatic progenitor cell differentiation and proliferation factor isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction in the 3' coding sequence compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AL121829
    Conserved Domains (1) summary
    pfam15060
    Location:145
    PPDFL; Differentiation and proliferation regulator
  2. NM_024299.3NP_077275.1  pancreatic progenitor cell differentiation and proliferation factor isoform 1

    See identical proteins and their annotated locations for NP_077275.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC002531, BP325433
    Consensus CDS
    CCDS13523.1
    UniProtKB/Swiss-Prot
    Q9H3Y8
    Related
    ENSP00000359198.3, OTTHUMP00000031562, ENST00000370179.7
    Conserved Domains (1) summary
    pfam15060
    Location:1110
    PPDFL; Differentiation and proliferation regulator

RNA

  1. NR_148427.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate exon compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AL121829, BF727015

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p12 Primary Assembly

    Range
    63520741..63522171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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