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RETREG2 reticulophagy regulator family member 2 [ Homo sapiens (human) ]

Gene ID: 79137, updated on 6-Oct-2018

Summary

Official Symbol
RETREG2provided by HGNC
Official Full Name
reticulophagy regulator family member 2provided by HGNC
Primary source
HGNC:HGNC:28450
See related
Ensembl:ENSG00000144567 Vega:OTTHUMG00000154577
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MAG-2; C2orf17; FAM134A
Expression
Ubiquitous expression in testis (RPKM 39.6), brain (RPKM 29.7) and 25 other tissues See more
Orthologs

Genomic context

See RETREG2 in Genome Data Viewer
Location:
2q35
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (219178190..219185475)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (220042939..220050197)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene non-homologous end joining factor 1 Neighboring gene RNA, 7SL, cytoplasmic 764, pseudogene Neighboring gene solute carrier family 23 member 3 Neighboring gene cyclin Pas1/PHO80 domain containing 1 Neighboring gene zinc finger AN1-type containing 2B Neighboring gene ATP binding cassette subfamily B member 6 (Langereis blood group)

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC3035, DKFZp686C2379

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
reticulophagy regulator 2
Names
family with sequence similarity 134 member A
metastasis associated gene-2
protein FAM134A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321109.1NP_001308038.1  reticulophagy regulator 2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC068946, BC002420, BC141851, BU615764, HY002817
  2. NM_001321110.1NP_001308039.1  reticulophagy regulator 2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC068946, AK091011, BU615764, DA172039
    UniProtKB/TrEMBL
    B3KR51
  3. NM_024293.5NP_077269.3  reticulophagy regulator 2 isoform 1

    See identical proteins and their annotated locations for NP_077269.3

    Status: VALIDATED

    Source sequence(s)
    AC068946, AL136758, BC141851, BG700888, BG723788, BU615764, HY002817
    Consensus CDS
    CCDS2434.1
    UniProtKB/Swiss-Prot
    Q8NC44
    Related
    ENSP00000395249.2, OTTHUMP00000206167, ENST00000430297.6, OTTHUMT00000336147

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

    Range
    219178190..219185475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005246848.3XP_005246905.1  reticulophagy regulator 2 isoform X1

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