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LAMC2 laminin subunit gamma 2 [ Equus caballus (horse) ]

Gene ID: 791245, updated on 3-Dec-2024

Summary

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Official Symbol
LAMC2provided by VGNC
Official Full Name
laminin subunit gamma 2provided by VGNC
Primary source
VGNC:VGNC:19568
See related
Ensembl:ENSECAG00000021903
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See LAMC2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (17461896..17514650)

Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene SHC binding and spindle associated 1 like Neighboring gene laminin subunit gamma 1 Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene uncharacterized LOC111773465

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009148.3 Chromosome 5 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Animal models for skin blistering conditions: absence of laminin 5 causes hereditary junctional mechanobullous disease in the Belgian horse. Spirito F, et al. J Invest Dermatol, 2002 Sep. PMID 12230513
  2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in morphogenesis of a polarized epithelium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tissue development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of laminin-5 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit gamma-2
Names
epiligrin subunit gamma
kalinin subunit gamma
laminin 5 gamma 2 subunit
laminin-5 subunit gamma
nicein subunit gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081768.2 → NP_001075237.2  laminin subunit gamma-2 precursor

    Status: VALIDATED

    Source sequence(s)
    PJAA01000006
    UniProtKB/Swiss-Prot
    Q8HZI9
    Related
    ENSECAP00000080214.1, ENSECAT00000087668.1

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009148.3 Reference EquCab3.0 Primary Assembly

    Range
    17461896..17514650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8HZI9.1 GenPept UniProtKB/Swiss-Prot:Q8HZI9

Gene LinkOut

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