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MEG8 maternally expressed 8, small nucleolar RNA host gene [ Homo sapiens (human) ]

Gene ID: 79104, updated on 31-Mar-2024

Summary

Official Symbol
MEG8provided by HGNC
Official Full Name
maternally expressed 8, small nucleolar RNA host geneprovided by HGNC
Primary source
HGNC:HGNC:14574
See related
MIM:613648; AllianceGenome:HGNC:14574
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Bsr; Irm; Rian; SNHG23; SNHG24; lnc-MGC; LINC00024; NCRNA00024
Summary
This gene is located in a cluster of imprinted genes on chromosome 14q32.3. It encodes a a non-protein coding transcript that is preferentially expressed from the maternal allele in skeletal muscle, and appears to be coordinately regulated with other imprinted genes in this region. [provided by RefSeq, Oct 2010]
Expression
Biased expression in adrenal (RPKM 3.1), placenta (RPKM 2.2) and 6 other tissues See more
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Genomic context

See MEG8 in Genome Data Viewer
Location:
14q32.2-q32.31
Exon count:
51
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (100889649..100999113)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (95125076..95234524)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (101355986..101465450)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 13483 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_33596 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_33604 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101357417-101357918 Neighboring gene retrotransposon Gag like 1 Neighboring gene microRNA 432 Neighboring gene microRNA 136 Neighboring gene small nucleolar RNA, C/D box 112 Neighboring gene microRNA 370 Neighboring gene small nucleolar RNA, C/D box 113-1 Neighboring gene small nucleolar RNA, C/D box 113-2 Neighboring gene small nucleolar RNA, C/D box 113-3 Neighboring gene small nucleolar RNA, C/D box 113-4 Neighboring gene small nucleolar RNA, C/D box 113-5 Neighboring gene small nucleolar RNA, C/D box 113-6 Neighboring gene small nucleolar RNA, C/D box 113-7 Neighboring gene small nucleolar RNA, C/D box 113-8 Neighboring gene small nucleolar RNA, C/D box 113-9 Neighboring gene small nucleolar RNA, C/D box 114-1 Neighboring gene small nucleolar RNA, C/D box 114-2 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene small nucleolar RNA, C/D box 114-3 Neighboring gene small nucleolar RNA, C/D box 114-4 Neighboring gene small nucleolar RNA, C/D box 114-5 Neighboring gene small nucleolar RNA, C/D box 114-6 Neighboring gene small nucleolar RNA, C/D box 114-7 Neighboring gene small nucleolar RNA, C/D box 114-8 Neighboring gene small nucleolar RNA, C/D box 114-10 Neighboring gene small nucleolar RNA, C/D box 114-9 Neighboring gene small nucleolar RNA, C/D box 114-11 Neighboring gene small nucleolar RNA, C/D box 114-12 Neighboring gene small nucleolar RNA, C/D box 114-13 Neighboring gene small nucleolar RNA, C/D box 114-14 Neighboring gene small nucleolar RNA, C/D box 114-15 Neighboring gene small nucleolar RNA, C/D box 114-16 Neighboring gene small nucleolar RNA, C/D box 114-17 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene small nucleolar RNA, C/D box 114-18 Neighboring gene small nucleolar RNA, C/D box 114-19 Neighboring gene uncharacterized LOC124903417 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene small nucleolar RNA, C/D box 114-20 Neighboring gene small nucleolar RNA, C/D box 114-21 Neighboring gene small nucleolar RNA, C/D box 114-22 Neighboring gene small nucleolar RNA, C/D box 114-23 Neighboring gene small nucleolar RNA, C/D box 114-24 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr14:101454444-101455643 Neighboring gene small nucleolar RNA, C/D box 114-25 Neighboring gene small nucleolar RNA, C/D box 114-26 Neighboring gene small nucleolar RNA, C/D box 114-27 Neighboring gene small nucleolar RNA, C/D box 114-28 Neighboring gene small nucleolar RNA, C/D box 114-29 Neighboring gene small nucleolar RNA, C/D box 114-30 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene small nucleolar RNA, C/D box 114-31 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr14:101467025-101468224 Neighboring gene mucin-2-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101474981-101475704 Neighboring gene microRNA 379 Neighboring gene microRNA 411

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • RNA Imprinted and Accumulated in Nucleus
  • imprinted RNA near Meg3/Gtl2
  • lncRNA microRNA megacluster host
  • long intergenic non-protein coding RNA 24
  • maternally expressed (in Callipyge) 8
  • small nucleolar RNA host gene 23 (non-protein coding)
  • small nucleolar RNA host gene 24 (non-protein coding)

Clone Names

  • AL132709.5, AL132709.8, DKFZp686L05266

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_045000.6 RefSeqGene

    Range
    58381..167845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_1058

RNA

  1. NR_146000.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL117190, AL132709

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    100889649..100999113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    95125076..95234524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_024149.2: Suppressed sequence

    Description
    NR_024149.2: This RefSeq was removed because it is now thought that this transcript is partial.
  2. NR_110178.1: Suppressed sequence

    Description
    NR_110178.1: This RefSeq was removed because it is now thought that this transcript is partial.