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MIR199A-1 microRNA mir-199a-1 [ Bos taurus (domestic cattle) ]

Gene ID: 790998, updated on 1-Feb-2025
Gene symbol
MIR199A-1
Gene description
microRNA mir-199a-1
See related
miRBase:MI0004758
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
MIRN199A; mir-199a-1; bta-mir-199a; bta-mir-199a-1
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See MIR199A-1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (39625344..39625447, complement)

Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene methyltransferase 13, eEF1A lysine and N-terminal methyltransferase Neighboring gene dynamin 3 Neighboring gene uncharacterized LOC132342463 Neighboring gene microRNA mir-3120 Neighboring gene microRNA mir-214 Neighboring gene chromosome 16 C1orf105 homolog Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene phosphatidylinositol glycan anchor biosynthesis class C

Genomic Sequence:
NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland. Gu Z, et al. FEBS Lett, 2007 Mar 6. PMID 17306260
  2. Characterization of bovine miRNAs by sequencing and bioinformatics analysis. Jin W, et al. BMC Mol Biol, 2009 Sep 16. PMID 19758457, Free PMC Article
  3. Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues. Coutinho LL, et al. Physiol Genomics, 2007 Mar 14. PMID 17105755
  4. miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, et al. Nucleic Acids Res, 2011 Jan. PMID 21037258, Free PMC Article
  5. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Other Names

  • microRNA 199A
  • microRNA 199a-1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_030908.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000016

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    39625344..39625447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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