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CCDC86 coiled-coil domain containing 86 [ Homo sapiens (human) ]

Gene ID: 79080, updated on 5-Jul-2020

Summary

Official Symbol
CCDC86provided by HGNC
Official Full Name
coiled-coil domain containing 86provided by HGNC
Primary source
HGNC:HGNC:28359
See related
Ensembl:ENSG00000110104 MIM:611293
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 26.3), adrenal (RPKM 10.0) and 25 other tissues See more
Orthologs

Genomic context

See CCDC86 in Genome Data Viewer
Location:
11q12.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (60842113..60851081)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (60609429..60618561)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene membrane spanning 4-domains A15 Neighboring gene uncharacterized LOC105369322 Neighboring gene membrane spanning 4-domains A10 Neighboring gene prostaglandin D2 receptor 2 Neighboring gene zona pellucida glycoprotein 1 Neighboring gene pre-mRNA processing factor 19

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC2574, FLJ22321

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
viral process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 86
Names
cyclon
cytokine-induced protein with coiled-coil domain

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024098.4NP_077003.1  coiled-coil domain-containing protein 86

    See identical proteins and their annotated locations for NP_077003.1

    Status: VALIDATED

    Source sequence(s)
    AP000777
    Consensus CDS
    CCDS7993.1
    UniProtKB/Swiss-Prot
    Q9H6F5
    Related
    ENSP00000227520.5, ENST00000227520.10
    Conserved Domains (2) summary
    pfam03879
    Location:236338
    Cgr1; Cgr1 family
    pfam05934
    Location:56201
    MCLC; Mid-1-related chloride channel (MCLC)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    60842113..60851081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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