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TMEM38A transmembrane protein 38A [ Homo sapiens (human) ]

Gene ID: 79041, updated on 22-Sep-2022

Summary

Official Symbol
TMEM38Aprovided by HGNC
Official Full Name
transmembrane protein 38Aprovided by HGNC
Primary source
HGNC:HGNC:28462
See related
Ensembl:ENSG00000072954 MIM:611235; AllianceGenome:HGNC:28462
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRICA; TRIC-A
Summary
Predicted to enable potassium channel activity. Predicted to act upstream of or within several processes, including cellular response to caffeine; inorganic cation transmembrane transport; and regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in brain (RPKM 7.4), stomach (RPKM 6.7) and 21 other tissues See more
Orthologs
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Genomic context

See TMEM38A in Genome Data Viewer
Location:
19p13.11
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (16661139..16690023)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (16795931..16824815)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (16771950..16800834)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372296 Neighboring gene uncharacterized LOC124904647 Neighboring gene small integral membrane protein 7 Neighboring gene NACHT and WD repeat domain containing 1 Neighboring gene uncharacterized LOC124904648 Neighboring gene SIN3 transcription regulator family member B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC3169

General protein information

Preferred Names
trimeric intracellular cation channel type A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024074.4NP_076979.1  trimeric intracellular cation channel type A

    See identical proteins and their annotated locations for NP_076979.1

    Status: VALIDATED

    Source sequence(s)
    AC008737, AC024075
    Consensus CDS
    CCDS12349.1
    UniProtKB/Swiss-Prot
    A8K9P9, Q9H6F2
    Related
    ENSP00000187762.1, ENST00000187762.7
    Conserved Domains (1) summary
    pfam05197
    Location:43225
    TRIC; TRIC channel

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    16661139..16690023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    16795931..16824815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)