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CAMKV CaM kinase like vesicle associated [ Homo sapiens (human) ]

Gene ID: 79012, updated on 23-Nov-2021

Summary

Official Symbol
CAMKVprovided by HGNC
Official Full Name
CaM kinase like vesicle associatedprovided by HGNC
Primary source
HGNC:HGNC:28788
See related
Ensembl:ENSG00000164076 MIM:614993
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
1G5; VACAMKL
Expression
Restricted expression toward brain (RPKM 33.0) See more
Orthologs
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Genomic context

See CAMKV in Genome Data Viewer
Location:
3p21.31
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49857989..49869906, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (49895422..49907339, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10954 Neighboring gene microRNA 5193 Neighboring gene ubiquitin like modifier activating enzyme 7 Neighboring gene TRAF interacting protein Neighboring gene RNA, 7SL, cytoplasmic 217, pseudogene Neighboring gene actin like 11, pseudogene Neighboring gene macrophage stimulating 1 receptor Neighboring gene uncharacterized LOC102724438

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC8407

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calmodulin-dependent protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of modification of postsynaptic structure IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
caM kinase-like vesicle-associated protein
Names
testis tissue sperm-binding protein Li 52e
vesicle-associated calmodulin-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320147.2NP_001307076.1  caM kinase-like vesicle-associated protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains a different 3' structure compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK074899, BC001921
    Consensus CDS
    CCDS82776.1
    UniProtKB/Swiss-Prot
    Q8NCB2
    UniProtKB/TrEMBL
    A0A024R331
    Related
    ENSP00000418809.1, ENST00000488336.5
    Conserved Domains (3) summary
    smart00220
    Location:24286
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    smart01104
    Location:347451
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    cd14088
    Location:22286
    STKc_CaMK_like; Catalytic domain of an Uncharacterized group of Serine/Threonine kinases with similarity to Calcium/calmodulin-dependent protein kinases
  2. NM_024046.5NP_076951.2  caM kinase-like vesicle-associated protein isoform 1

    See identical proteins and their annotated locations for NP_076951.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK074856, BC017363
    Consensus CDS
    CCDS33762.1
    UniProtKB/Swiss-Prot
    Q8NCB2
    UniProtKB/TrEMBL
    A0A140VKD5
    Related
    ENSP00000419195.1, ENST00000477224.6
    Conserved Domains (2) summary
    smart00220
    Location:24286
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14088
    Location:22286
    STKc_CaMK_like; Catalytic domain of an Uncharacterized group of Serine/Threonine kinases with similarity to Calcium/calmodulin-dependent protein kinases

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49857989..49869906 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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