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CUEDC2 CUE domain containing 2 [ Homo sapiens (human) ]

Gene ID: 79004, updated on 13-Mar-2020

Summary

Official Symbol
CUEDC2provided by HGNC
Official Full Name
CUE domain containing 2provided by HGNC
Primary source
HGNC:HGNC:28352
See related
Ensembl:ENSG00000107874 MIM:614142
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf66; bA18I14.5
Expression
Ubiquitous expression in brain (RPKM 31.2), heart (RPKM 24.6) and 25 other tissues See more
Orthologs

Genomic context

See CUEDC2 in Genome Data Viewer
Location:
10q24.32
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (102423249..102432574, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (104183002..104192423, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene nuclear factor kappa B subunit 2 Neighboring gene pleckstrin and Sec7 domain containing Neighboring gene F-box and leucine rich repeat protein 15 Neighboring gene microRNA 146b Neighboring gene RPARP antisense RNA 1 Neighboring gene chromosome 10 open reading frame 95

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A Genome-wide Association Study of Autism Using the Simons Simplex Collection: Does Reducing Phenotypic Heterogeneity in Autism Increase Genetic Homogeneity?
NHGRI GWA Catalog
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC2491

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nuclear membrane IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
CUE domain-containing protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024040.3NP_076945.2  CUE domain-containing protein 2

    See identical proteins and their annotated locations for NP_076945.2

    Status: VALIDATED

    Source sequence(s)
    BC000262, CX165866
    Consensus CDS
    CCDS41566.1
    UniProtKB/Swiss-Prot
    Q9H467
    Related
    ENSP00000358953.4, ENST00000369937.5
    Conserved Domains (1) summary
    cd14367
    Location:147186
    CUE_CUED2; CUE domain found in CUE domain-containing protein 2 (CUED2) and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    102423249..102432574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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