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WDTC1 WD and tetratricopeptide repeats 1 [ Bos taurus (domestic cattle) ]

Gene ID: 789937, updated on 27-Dec-2024

Summary

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Official Symbol
WDTC1provided by VGNC
Official Full Name
WD and tetratricopeptide repeats 1provided by VGNC
Primary source
VGNC:VGNC:107027
See related
Ensembl:ENSBTAG00000053588
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See WDTC1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (125969836..126037062, complement)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin like 1 Neighboring gene transmembrane protein 222 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene solute carrier family 9 member A1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
WD and tetratricopeptide repeats protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205398.2 → NP_001192327.1  WD and tetratricopeptide repeats protein 1

    See identical proteins and their annotated locations for NP_001192327.1

    Status: VALIDATED

    Source sequence(s)
    DT816337, EE341576, NKLS02000002
    UniProtKB/TrEMBL
    A0A3Q1LPL4
    Related
    ENSBTAP00000062024.2, ENSBTAT00000070605.2
    Conserved Domains (4) summary
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl26005
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    125969836..126037062 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024978597.2 → XP_024834365.1  WD and tetratricopeptide repeats protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1LPL4
    Conserved Domains (4) summary
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl26005
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

  2. XM_059877376.1 → XP_059733359.1  WD and tetratricopeptide repeats protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LPL4, A0AAA9RSU6

  3. XM_024978608.2 → XP_024834376.1  WD and tetratricopeptide repeats protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LPL4
    Conserved Domains (4) summary
    sd00006
    Location:365 → 389
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl26005
    Location:367 → 437
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

  4. XM_059877379.1 → XP_059733362.1  WD and tetratricopeptide repeats protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LPL4
    Related
    ENSBTAP00000099451.1, ENSBTAT00000100266.1

  5. XM_059877380.1 → XP_059733363.1  WD and tetratricopeptide repeats protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LPL4

  6. XM_059877364.1 → XP_059733347.1  WD and tetratricopeptide repeats protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LPL4, A0AAA9RSU6
    Related
    ENSBTAP00000075775.1, ENSBTAT00000122526.1

  7. XM_059877368.1 → XP_059733351.1  WD and tetratricopeptide repeats protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LPL4, A0AAA9RSU6
Nucleotide Protein Strain
Heading Accession and Version

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