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Avl9 AVL9 cell migration associated [ Mus musculus (house mouse) ]

Gene ID: 78937, updated on 5-Mar-2024

Summary

Official Symbol
Avl9provided by MGI
Official Full Name
AVL9 cell migration associatedprovided by MGI
Primary source
MGI:MGI:1926187
See related
Ensembl:ENSMUSG00000029787 AllianceGenome:MGI:1926187
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0241; 5830411G16Rik; D730049P16Rik
Summary
Predicted to be involved in cell migration. Predicted to be located in recycling endosome. Predicted to be active in cytoplasm. Is expressed in nervous system and sensory organ. Orthologous to human AVL9 (AVL9 cell migration associated). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 9.7), CNS E14 (RPKM 8.9) and 28 other tissues See more
Orthologs
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Genomic context

Location:
6 B3; 6 27.72 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (56691720..56738897)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (56714839..56761912)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 1C Neighboring gene STARR-seq mESC enhancer starr_15989 Neighboring gene predicted gene, 22493 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:56654682-56654884 Neighboring gene STARR-seq mESC enhancer starr_15990 Neighboring gene STARR-positive B cell enhancer ABC_E679 Neighboring gene LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene STARR-seq mESC enhancer starr_15991 Neighboring gene STARR-positive B cell enhancer ABC_E4829 Neighboring gene STARR-seq mESC enhancer starr_15993 Neighboring gene kelch repeat and BTB (POZ) domain containing 2 Neighboring gene predicted gene 10209 Neighboring gene FK506 binding protein 9

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in recycling endosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
late secretory pathway protein AVL9 homolog
Names
AVL9 homolog (S. cerevisiase)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030235.1NP_084511.1  late secretory pathway protein AVL9 homolog

    See identical proteins and their annotated locations for NP_084511.1

    Status: VALIDATED

    Source sequence(s)
    AK122228, CJ109208
    Consensus CDS
    CCDS51789.1
    UniProtKB/Swiss-Prot
    Q149B3, Q80U56
    Related
    ENSMUSP00000031805.9, ENSMUST00000031805.11
    Conserved Domains (4) summary
    pfam07792
    Location:1676
    Afi1; Docking domain of Afi1 for Arf3 in vesicle trafficking
    pfam08616
    Location:382459
    SPA; Stabilization of polarity axis
    pfam09794
    Location:16521
    Avl9; Transport protein Avl9
    cl11519
    Location:116226
    DENN; DENN (AEX-3) domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    56691720..56738897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152408.1XP_036008301.1  late secretory pathway protein AVL9 homolog isoform X1

    Conserved Domains (1) summary
    pfam09794
    Location:16521
    Avl9; Transport protein Avl9
  2. XM_036152409.1XP_036008302.1  late secretory pathway protein AVL9 homolog isoform X2

    Conserved Domains (1) summary
    cl40632
    Location:166303
    Avl9; Transport protein Avl9
  3. XM_006506790.3XP_006506853.1  late secretory pathway protein AVL9 homolog isoform X3

    Conserved Domains (1) summary
    pfam09794
    Location:166303
    Avl9; Transport protein Avl9