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Gins3 GINS complex subunit 3 [ Mus musculus (house mouse) ]

Gene ID: 78833, updated on 5-Mar-2024

Summary

Official Symbol
Gins3provided by MGI
Official Full Name
GINS complex subunit 3provided by MGI
Primary source
MGI:MGI:1926083
See related
Ensembl:ENSMUSG00000031669 AllianceGenome:MGI:1926083
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Psf3; 2700085M18Rik
Summary
Predicted to be involved in mitotic DNA replication initiation. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of GINS complex. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human GINS3 (GINS complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 5.4), liver E14 (RPKM 3.9) and 23 other tissues See more
Orthologs
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Genomic context

Location:
8 D1; 8 47.12 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (96360187..96371687)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (95633559..95645059)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene G patch domain and KOW motifs pseudogene Neighboring gene STARR-seq mESC enhancer starr_22391 Neighboring gene predicted gene, 31518 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:98157360-98157469 Neighboring gene predicted gene, 39230 Neighboring gene predicted gene, 42037

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA unwinding involved in DNA replication ISO
Inferred from Sequence Orthology
more info
 
involved_in DNA unwinding involved in DNA replication NAS
Non-traceable Author Statement
more info
PubMed 
involved_in mitotic DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of CMG complex ISO
Inferred from Sequence Orthology
more info
 
part_of GINS complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of GINS complex ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
DNA replication complex GINS protein PSF3
Names
GINS complex subunit 3 (Psf3 homolog)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030198.3NP_084474.1  DNA replication complex GINS protein PSF3

    See identical proteins and their annotated locations for NP_084474.1

    Status: PROVISIONAL

    Source sequence(s)
    AC113951
    Consensus CDS
    CCDS22564.1
    UniProtKB/Swiss-Prot
    Q9CY94
    Related
    ENSMUSP00000034094.9, ENSMUST00000034094.11
    Conserved Domains (1) summary
    cd11713
    Location:83192
    GINS_A_psf3; Alpha-helical domain of GINS complex protein Psf3 (partner of Sld5 3)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    96360187..96371687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)