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Tsc22d4 Tsc22 domain family, member 4 [ Mus musculus (house mouse) ]

Gene ID: 78829, updated on 5-Mar-2024

Summary

Official Symbol
Tsc22d4provided by MGI
Official Full Name
Tsc22 domain family, member 4provided by MGI
Primary source
MGI:MGI:1926079
See related
Ensembl:ENSMUSG00000029723 AllianceGenome:MGI:1926079
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tilz2; Spacdr; AI415410; Thg-1pit; 0610009M14Rik; 1700023B23Rik
Summary
Acts upstream of or within response to osmotic stress. Located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; genitourinary system; and nervous system. Orthologous to several human genes including TSC22D4 (TSC22 domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 94.0), heart adult (RPKM 40.5) and 27 other tissues See more
Orthologs
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Genomic context

See Tsc22d4 in Genome Data Viewer
Location:
5 G2; 5 76.64 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137744274..137758011)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137745969..137768453)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54308 Neighboring gene Sp110 nuclear body protein, pseudogene 2 Neighboring gene neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1 Neighboring gene predicted gene, 57848 Neighboring gene sperm acrosome developmental regulator Neighboring gene STARR-positive B cell enhancer ABC_E4797 Neighboring gene protein phosphatase 1, regulatory subunit 35

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough Gm57848

Readthrough gene: Gm57848, Included gene: Spacdr

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in response to osmotic stress IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within response to osmotic stress IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in acrosomal vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
TSC22 domain family protein 4
Names
TSC22 domain family 4
TSC22-related inducible leucine zipper 2
TSC22-related-inducible leucine zipper protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023910.7NP_076399.4  TSC22 domain family protein 4

    See identical proteins and their annotated locations for NP_076399.4

    Status: VALIDATED

    Source sequence(s)
    AC125063
    Consensus CDS
    CCDS19776.1
    UniProtKB/Swiss-Prot
    Q99PD5, Q9D2V9, Q9EQN3
    UniProtKB/TrEMBL
    Q3U4M0, Q8BYC5
    Related
    ENSMUSP00000098107.4, ENSMUST00000100539.10
    Conserved Domains (1) summary
    pfam01166
    Location:318372
    TSC22; TSC-22/dip/bun family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    137744274..137758011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)