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Spacdr sperm acrosome developmental regulator [ Mus musculus (house mouse) ]

Gene ID: 78829, updated on 11-Mar-2023

Summary

Official Symbol
Spacdrprovided by MGI
Official Full Name
sperm acrosome developmental regulatorprovided by MGI
Primary source
MGI:MGI:1926079
See related
Ensembl:ENSMUSG00000029723 AllianceGenome:MGI:1926079
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tilz2; Tsc22d4; Thg-1pit; 0610009M14Rik; 1700023B23Rik
Summary
Acts upstream of or within response to osmotic stress. Located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; genitourinary system; and nervous system. Orthologous to several human genes including TSC22D4 (TSC22 domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 94.0), heart adult (RPKM 40.5) and 27 other tissues See more
Orthologs
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Genomic context

See Spacdr in Genome Data Viewer
Location:
5; 5 G2
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137744231..137766715)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137745969..137768453)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54308 Neighboring gene predicted gene 15753 Neighboring gene neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1 Neighboring gene protein phosphatase 1, regulatory subunit 35 Neighboring gene methylphosphate capping enzyme

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough LOC122152371

Readthrough gene: LOC122152371, Included gene: LOC122152370

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in acrosomal vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sperm acrosome developmental regulator
Names
TSC22 domain family 4
TSC22 domain family protein 4
TSC22 domain family, member 4
TSC22-related inducible leucine zipper 2
TSC22-related-inducible leucine zipper protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023910.7NP_076399.4  sperm acrosome developmental regulator

    See identical proteins and their annotated locations for NP_076399.4

    Status: VALIDATED

    Source sequence(s)
    AC125063
    Consensus CDS
    CCDS19776.1
    UniProtKB/Swiss-Prot
    Q9D2V9, Q9EQN3
    Related
    ENSMUSP00000098107.4, ENSMUST00000100539.10
    Conserved Domains (1) summary
    pfam01166
    Location:318372
    TSC22; TSC-22/dip/bun family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    137744231..137766715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)