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Mctp1 multiple C2 domains, transmembrane 1 [ Mus musculus (house mouse) ]

Gene ID: 78771, updated on 9-Sep-2018

Summary

Official Symbol
Mctp1provided by MGI
Official Full Name
multiple C2 domains, transmembrane 1provided by MGI
Primary source
MGI:MGI:1926021
See related
Ensembl:ENSMUSG00000021596 Vega:OTTMUSG00000025745
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810465F10Rik
Expression
Biased expression in cerebellum adult (RPKM 5.3), ovary adult (RPKM 4.5) and 9 other tissues See more
Orthologs

Genomic context

See Mctp1 in Genome Data Viewer
Location:
13; 13 C1
Exon count:
26
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (76384108..77033277)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (76522409..77171071)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 81, member B Neighboring gene predicted gene, 31219 Neighboring gene predicted gene, 31516 Neighboring gene SCAN domain containing 3 pseudogene Neighboring gene predicted gene, 46431 Neighboring gene vacuolar protein sorting 4a pseudogene Neighboring gene jagunal homolog 1 pseudogene Neighboring gene chromatin modifying protein 2A pseudogene Neighboring gene RIKEN cDNA 2210408I21 gene Neighboring gene SMC5-SMC6 complex localization factor 1 Neighboring gene predicted gene, 29844 Neighboring gene NSA2 ribosome biogenesis homolog pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
negative regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endocytosis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
regulation of neurotransmitter secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endosome IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
recycling endosome ISO
Inferred from Sequence Orthology
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
multiple C2 and transmembrane domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030174.2NP_084450.2  multiple C2 and transmembrane domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AK047562, BB197311, CD352795
    Consensus CDS
    CCDS26656.1
    UniProtKB/TrEMBL
    E9PW38, Q8C8C0
    Related
    ENSMUSP00000105212.2, ENSMUST00000109583.8
    Conserved Domains (4) summary
    cd04042
    Location:3124
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:166281
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:321439
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:582667
    PRT_C; Plant phosphoribosyltransferase C-terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    76384108..77033277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517462.3XP_006517525.3  multiple C2 and transmembrane domain-containing protein 1 isoform X1

  2. XM_006517466.3XP_006517529.3  multiple C2 and transmembrane domain-containing protein 1 isoform X5

  3. XM_006517464.3XP_006517527.3  multiple C2 and transmembrane domain-containing protein 1 isoform X3

  4. XM_006517463.3XP_006517526.3  multiple C2 and transmembrane domain-containing protein 1 isoform X2

  5. XM_017315642.1XP_017171131.1  multiple C2 and transmembrane domain-containing protein 1 isoform X4

    UniProtKB/Swiss-Prot
    E9PV86
    Related
    ENSMUSP00000118958.1, OTTMUSP00000031345, ENSMUST00000125209.7, OTTMUST00000063420
    Conserved Domains (4) summary
    cd04042
    Location:260381
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:423538
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:578696
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:839924
    PRT_C; Plant phosphoribosyltransferase C-terminal
  6. XM_006517467.3XP_006517530.3  multiple C2 and transmembrane domain-containing protein 1 isoform X6

  7. XM_017315643.1XP_017171132.1  multiple C2 and transmembrane domain-containing protein 1 isoform X7

  8. XM_006517472.3XP_006517535.3  multiple C2 and transmembrane domain-containing protein 1 isoform X13

  9. XM_006517468.3XP_006517531.1  multiple C2 and transmembrane domain-containing protein 1 isoform X8

    Conserved Domains (4) summary
    cd04042
    Location:40161
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:239354
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:394512
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:655740
    PRT_C; Plant phosphoribosyltransferase C-terminal
  10. XM_017315644.1XP_017171133.1  multiple C2 and transmembrane domain-containing protein 1 isoform X12

  11. XM_006517469.3XP_006517532.1  multiple C2 and transmembrane domain-containing protein 1 isoform X9

    Conserved Domains (4) summary
    cd04042
    Location:40161
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:223338
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:378496
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:639724
    PRT_C; Plant phosphoribosyltransferase C-terminal
  12. XM_006517471.3XP_006517534.1  multiple C2 and transmembrane domain-containing protein 1 isoform X11

    Conserved Domains (4) summary
    cd04042
    Location:40161
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:190305
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:345463
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:606691
    PRT_C; Plant phosphoribosyltransferase C-terminal
  13. XM_006517470.3XP_006517533.1  multiple C2 and transmembrane domain-containing protein 1 isoform X10

    See identical proteins and their annotated locations for XP_006517533.1

    Conserved Domains (4) summary
    cd04042
    Location:3124
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:202317
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:357475
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:618703
    PRT_C; Plant phosphoribosyltransferase C-terminal
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