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Pgpep1l pyroglutamyl-peptidase I-like [ Mus musculus (house mouse) ]

Gene ID: 78444, updated on 31-Jan-2019

Summary

Official Symbol
Pgpep1lprovided by MGI
Official Full Name
pyroglutamyl-peptidase I-likeprovided by MGI
Primary source
MGI:MGI:1925694
See related
Ensembl:ENSMUSG00000030553
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C330024D12Rik
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See Pgpep1l in Genome Data Viewer
Location:
7; 7 C
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (68236450..68264484, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (75381494..75409119, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39027 Neighboring gene insulin-like growth factor I receptor Neighboring gene predicted gene 16157 Neighboring gene family with sequence similarity 169, member B Neighboring gene predicted gene 16158

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
pyroglutamyl-peptidase 1-like protein
NP_084377.1
XP_006541378.1
XP_017167887.1
XP_017167888.1
XP_017167889.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030101.1NP_084377.1  pyroglutamyl-peptidase 1-like protein

    Status: VALIDATED

    Source sequence(s)
    AC101879, AK021221, BY728828
    Consensus CDS
    CCDS52271.1
    UniProtKB/Swiss-Prot
    Q9CWB5
    UniProtKB/TrEMBL
    E9QM76
    Related
    ENSMUSP00000032770.2, ENSMUST00000032770.3
    Conserved Domains (1) summary
    cl00237
    Location:397
    Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    68236450..68264484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541315.2XP_006541378.1  pyroglutamyl-peptidase 1-like protein isoform X2

    Related
    ENSMUSP00000146996.1, ENSMUST00000207874.1
    Conserved Domains (1) summary
    cd00501
    Location:6188
    Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...
  2. XM_017312399.1XP_017167888.1  pyroglutamyl-peptidase 1-like protein isoform X3

  3. XM_017312398.1XP_017167887.1  pyroglutamyl-peptidase 1-like protein isoform X1

  4. XM_017312400.1XP_017167889.1  pyroglutamyl-peptidase 1-like protein isoform X4

    Conserved Domains (1) summary
    cl00237
    Location:18140
    Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...
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