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Ndufv3 NADH:ubiquinone oxidoreductase core subunit V3 [ Mus musculus (house mouse) ]

Gene ID: 78330, updated on 5-Mar-2024

Summary

Official Symbol
Ndufv3provided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase core subunit V3provided by MGI
Primary source
MGI:MGI:1890894
See related
Ensembl:ENSMUSG00000024038 AllianceGenome:MGI:1890894
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500032D16Rik
Summary
Predicted to be involved in mitochondrial ATP synthesis coupled electron transport. Located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human NDUFV3 (NADH:ubiquinone oxidoreductase subunit V3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 60.1), kidney adult (RPKM 42.8) and 28 other tissues See more
Orthologs
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Genomic context

See Ndufv3 in Genome Data Viewer
Location:
17 B1; 17 16.64 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (31739089..31750300)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (31520115..31531326)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 9A Neighboring gene predicted gene 9902 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:31649222-31649405 Neighboring gene WD repeat domain 4 Neighboring gene STARR-positive B cell enhancer ABC_E3197 Neighboring gene STARR-positive B cell enhancer ABC_E9439 Neighboring gene predicted gene, 50105 Neighboring gene Pbx/knotted 1 homeobox Neighboring gene STARR-seq mESC enhancer starr_42341

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in respirasome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Names
CI-9kD
NADH dehydrogenase (ubiquinone) flavoprotein 3
NADH-ubiquinone oxidoreductase 9 kDa subunit
NADH-ubiquinone oxidoreductase flavoprotein 3
complex I-9kD
NP_001077360.1
NP_084363.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083891.1NP_001077360.1  NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform 2

    See identical proteins and their annotated locations for NP_001077360.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AK077433, BU555486, BU755401
    Consensus CDS
    CCDS37550.1
    UniProtKB/Swiss-Prot
    Q8BK30
    Related
    ENSMUSP00000066303.9, ENSMUST00000064798.16
    Conserved Domains (1) summary
    pfam15880
    Location:6397
    NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
  2. NM_030087.2NP_084363.2  NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform 1

    See identical proteins and their annotated locations for NP_084363.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC166172, BF318157, BU555486, BU755401, BY064612
    Consensus CDS
    CCDS37549.1
    UniProtKB/TrEMBL
    Q3U422, Q91WP8
    Related
    ENSMUSP00000049000.9, ENSMUST00000046288.16
    Conserved Domains (1) summary
    pfam15880
    Location:427460
    NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    31739089..31750300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)