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CXCR2 C-X-C motif chemokine receptor 2 [ Bos taurus (domestic cattle) ]

Gene ID: 782719, updated on 20-Feb-2025
Gene symbol
CXCR2
Gene description
C-X-C motif chemokine receptor 2
See related
BGD:BT24328; EnsemblRapid:ENSBTAG00070002617
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
IL8RB; CXC-R2; CXCR-2
Orthologs
human mouse all
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See CXCR2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (106184638..106194129)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene tensin 1 Neighboring gene uncharacterized LOC132343295 Neighboring gene RUN and FYVE domain containing 4 Neighboring gene uncharacterized LOC132343296 Neighboring gene chemokine (C-X-C motif) receptor 1

Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. [Study on the relationships between polymorphisms of CXCR2 gene and milk quality and mastitis of dairy cow]. Xu M, et al. Yi Chuan, 2008 Apr. PMID 18424417
  2. Identification and characterization of a new interleukin-8 receptor in bovine species. Lahouassa H, et al. Mol Immunol, 2008 Feb. PMID 17727952
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables C-C chemokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables C-C chemokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables C-X-C chemokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-8 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
C-X-C chemokine receptor type 2
Names
IL-8R B
chemokine receptor CXCR2
high affinity interleukin-8 receptor B
interleukin 8 receptor, alpha
interleukin 8 receptor, beta

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101285.1 → NP_001094755.1  C-X-C chemokine receptor type 2

    See identical proteins and their annotated locations for NP_001094755.1

    Status: PROVISIONAL

    Source sequence(s)
    EF634483
    UniProtKB/TrEMBL
    A0AAA9S8Q6, A6YM52
    Related
    ENSBTAP00070003510.1, ENSBTAT00070006056.1
    Conserved Domains (1) summary
    cd15178
    Location:53 → 328
    7tmA_CXCR1_2; CXC chemokine receptor types 1 and 2, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    106184638..106194129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024978406.1 → XP_024834174.1  C-X-C chemokine receptor type 2 isoform X1

    UniProtKB/TrEMBL
    A0AAA9S8Q6
    Conserved Domains (1) summary
    cd15178
    Location:90 → 365
    7tmA_CXCR1_2; CXC chemokine receptor types 1 and 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_024978410.2 → XP_024834178.1  C-X-C chemokine receptor type 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MHN9, A0AAA9S8Q6
    Related
    ENSBTAP00070003511.1, ENSBTAT00070006060.1
    Conserved Domains (1) summary
    cd15178
    Location:77 → 352
    7tmA_CXCR1_2; CXC chemokine receptor types 1 and 2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_059877164.1 → XP_059733147.1  C-X-C chemokine receptor type 2 isoform X3

    UniProtKB/TrEMBL
    J3QY08
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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