phkg2 phosphorylase kinase, gamma 2 (testis) [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: phkg2provided by Xenbase
Official Full Name: phosphorylase kinase, gamma 2 (testis)provided by Xenbase
Primary source: Xenbase:XB-GENE-994728
See related: Ensembl:ENSXETG00000021132 AllianceGenome:Xenbase:XB-GENE-994728
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable phosphorylase kinase activity. Predicted to be involved in glycogen metabolic process and signal transduction. Predicted to be part of phosphorylase kinase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXc; and liver cirrhosis. Orthologous to human PHKG2 (phosphorylase kinase catalytic subunit gamma 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	9	NC_030685.2 (13714427..13724485, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	9	NC_030685.1 (8049683..8062075, complement)

Chromosome 9 - NC_030685.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables calmodulin binding	IEA Inferred from Electronic Annotation more info
enables phosphorylase kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphorylase kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glycogen metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glycogen metabolic process	IEA Inferred from Electronic Annotation more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of phosphorylase kinase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of phosphorylase kinase complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: phosphorylase b kinase gamma catalytic chain, liver/testis isoform

NP_001072287.1

EC 2.7.11.19

XP_012825992.1

EC 2.7.11.19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001078819.1 → NP_001072287.1 phosphorylase b kinase gamma catalytic chain, liver/testis isoform

See identical proteins and their annotated locations for NP_001072287.1

Status: PROVISIONAL

Source sequence(s)

BC121313

UniProtKB/TrEMBL

A0A6I8R6L8, Q0VA11

Related

ENSXETP00000076823.2, ENSXETT00000068654.2

Conserved Domains (1) summary

cl21453
Location:13 → 216

PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

13714427..13724485 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012970538.3 → XP_012825992.1 phosphorylase b kinase gamma catalytic chain, liver/testis isoform isoform X1

UniProtKB/TrEMBL

F6UTW9

Related

ENSXETP00000045687.5, ENSXETT00000045687.5

Conserved Domains (1) summary

cd14181
Location:13 → 291

STKc_PhKG2; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma 2 subunit