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ZXDA zinc finger X-linked duplicated A [ Homo sapiens (human) ]

Gene ID: 7789, updated on 27-Nov-2024

Summary

Official Symbol
ZXDAprovided by HGNC
Official Full Name
zinc finger X-linked duplicated Aprovided by HGNC
Primary source
HGNC:HGNC:13198
See related
Ensembl:ENSG00000198205 MIM:300235; AllianceGenome:HGNC:13198
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF896
Summary
This gene encodes one of two duplicated zinc finger genes on chromosome Xp11. This gene is the telomeric copy; GeneID 158586 ZXDB is the more centromeric copy. The two genes have 98% nucleotide sequence similarity, and the predicted proteins contain 10 tandem zinc finger motifs. [provided by RefSeq, Nov 2009]
Orthologs
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Genomic context

See ZXDA in Genome Data Viewer
Location:
Xp11.21
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (57905430..57910458, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (57205099..57210129, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (57931864..57936892, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene MDH1 pseudogene 1 Neighboring gene uncharacterized LOC124905232 Neighboring gene Sharpr-MPRA regulatory region 7453 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20873 Neighboring gene MYCL pseudogene 2 Neighboring gene keratin 8 pseudogene 17

Genomic regions, transcripts, and products

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables C2H2 zinc finger domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription coactivator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger X-linked protein ZXDA
Names
zinc finger protein 896

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_015974.1 RefSeqGene

    Range
    5176..10204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_007156.5NP_009087.1  zinc finger X-linked protein ZXDA

    See identical proteins and their annotated locations for NP_009087.1

    Status: REVIEWED

    Source sequence(s)
    AL034396
    Consensus CDS
    CCDS14376.1
    UniProtKB/Swiss-Prot
    P98168, Q9UJP7
    UniProtKB/TrEMBL
    A8K9H1
    Related
    ENSP00000351530.4, ENST00000358697.6
    Conserved Domains (6) summary
    COG5048
    Location:437568
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:425444
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:512534
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:300324
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:346369
    zf-H2C2_2; Zinc-finger double domain
    pfam17017
    Location:300445
    zf-C2H2_aberr; Aberrant zinc-finger

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    57905430..57910458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    57205099..57210129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)