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Lrrc42 leucine rich repeat containing 42 [ Mus musculus (house mouse) ]

Gene ID: 77809, updated on 5-Mar-2024

Summary

Official Symbol
Lrrc42provided by MGI
Official Full Name
leucine rich repeat containing 42provided by MGI
Primary source
MGI:MGI:1925059
See related
Ensembl:ENSMUSG00000028617 AllianceGenome:MGI:1925059
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A930011F22Rik
Summary
Is expressed in cranium; jaw; tail dorsal root ganglion; and ventral grey horn. Orthologous to human LRRC42 (leucine rich repeat containing 42). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 16.7), limb E14.5 (RPKM 15.6) and 28 other tissues See more
Orthologs
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Genomic context

Location:
4 C7; 4 50.18 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (107090711..107110730, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (107233514..107253533, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 59 Neighboring gene low density lipoprotein receptor class A domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E4642 Neighboring gene intraflagellar transport 25 Neighboring gene Yip1 domain family, member 1 Neighboring gene deiodinase, iodothyronine, type I

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
leucine-rich repeat-containing protein 42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029985.2NP_084261.1  leucine-rich repeat-containing protein 42

    See identical proteins and their annotated locations for NP_084261.1

    Status: VALIDATED

    Source sequence(s)
    BC027203, BX632859, CJ174174
    Consensus CDS
    CCDS18434.1
    UniProtKB/Swiss-Prot
    Q3TE62, Q8R2U7, Q9CTP9
    Related
    ENSMUSP00000030360.5, ENSMUST00000030360.11
    Conserved Domains (2) summary
    cd00116
    Location:167272
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:150174
    LRR_AMN1; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    107090711..107110730 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164551.1XP_036020444.1  leucine-rich repeat-containing protein 42 isoform X1